| thyrotoxic coma | Coma preceding death in severe hyperthyroidism, as in thyroid storm or thyrotoxic crisis. (05 Mar 2000) |
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| thyrotoxic | Denoting thyrotoxicosis. (05 Mar 2000) |
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| thyrotoxic complement-fixation factor | A form of thyrotoxin; an antigen found most readily in thyroid tissue from thyrotoxic individuals; known to be chemically and immunologically distinct from thyroglobulin, and fixes complement when combined with antibody related to the gamma-globulin fraction of serum. With the exception of extremely small concentrations, the antigen is rarely found in normal glands or in diseased glands that are not associated with thyrotoxicosis; it is probably an intracellular substance (possibly a constituent of the "microsomal fraction"), and does not contain iodine in significant quantity. Not related to the complement-fixation reaction occurring with serum in Hashimoto's disease, in which the antigen is thyroglobulin. (05 Mar 2000) |
| thyrotoxic crisis | Thyroid crisis, the exacerbation of symptoms that occurs in severe thyrotoxicosis; can follow shock or injury or thyroidectomy; marked by rapid pulse (140 to 170 per minute), nausea, diarrhoea, fever, loss of weight, extreme nervousness, and a sudden rise in the metabolic rate; coma and death may occur; occasionally the entire clinical picture is that of profound prostration, weakness, and collapse, without the phase of muscular overactivity and tachycardia. Synonym: thyroid storm. (05 Mar 2000) |
| thyrotoxic encephalopathy | A metabolic encephalopathy arising in severe cases of thyrotoxicosis. (05 Mar 2000) |
| thyrotoxic heart disease | Cardiac symptoms, signs, and physiologic impairment due to overactivity of the thyroid gland usually due to excessive sympathetic stimulation. (05 Mar 2000) |
| thyrotoxic myopathy | Extreme muscular weakness in severe thyrotoxicosis affecting muscles of limbs and trunk as well as those used in speech and swallowing. (05 Mar 2000) |
| thyrotoxic serum | An antiserum obtained by injecting into animals the nucleoproteins of the thyroid gland. (05 Mar 2000) |
| glasgow coma scale | A scale that assesses the degree of coma in patients with craniocerebral injuries; also assesses brain function, brain damage, and patient progress. (12 Dec 1998) |
| metabolic coma | Coma resulting from diffuse failure of neuronal metabolism, caused by such abnormalities as intrinsic disorders of neuron or glial cell metabolism, or extracerebral disorders that produce intoxication or electrolyte imbalances. (05 Mar 2000) |
| coma | A deep prolonged unconsciousness where the patient cannot be aroused. This is usually as the result of a head injury, neurological disease, acute hydrocephaly, intoxication or metabolic derangement. (27 Sep 1997) |
| coma aberration | The distortion of image formation created when a bundle of light rays enters an optical system not parallel to the optic axis. <botany> Any tuft, as the hairs on a seed, or the greenery on a radish or a pineapple. Synonym: coma. Origin: G. Kome, hair, foliage (05 Mar 2000) |
| coma carcinomatosum | Coma occurring in the final stage of cancerous cachexia. (05 Mar 2000) |
| coma cast | A renal cast of strongly refracting granules said to be indicative of imminent coma in diabetes. Synonym: Kulz's cylinder. (05 Mar 2000) |
| coma scale | A clinical scale to assess impaired consciousness; assessment may include motor responsiveness, verbal performance, and eye opening, as in the Glasgow (Scotland) c.s., or the same three items and dysfunction of cranial nerves, as in the Maryland (U.S.) c.s. (05 Mar 2000) |
| coma vigil | Subacute or chronic state of altered consciousness, in which the patient appears alert intermittently, but is not responsive, although his/her descending motor pathways appear intact; due to lesions of various cerebral structures. Synonym: coma vigil. (05 Mar 2000) |