| thyroid nodule | A small circumscribed mass of differentiated tissue associated with the thyroid gland. It can be pathogenic or non-pathogenic. The growth of nodules can lead to a condition of goiter, nodular. most nodules appear between the ages of 30 and 50 years and most are benign. (12 Dec 1998) |
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| cold thyroid nodule | <radiology> Adenoma (75%), colloid cyst (10%), carcinoma (15%), mnemonic: CATCH PALLM colloid cyst, adenoma, thyroiditis, carcinoma, haematoma, parathyroid adenoma, abscess, lymph node, lymphoma, metastasis thyroid carcinoma, hot thyroid nodule (12 Dec 1998) |
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| hot thyroid nodule | <radiology> Almost always hyperfunctioning adenoma, vast majority benign, up to 50% are autonomous see also: thyroid carcinoma, cold thyroid nodule (12 Dec 1998) |
| discordant thyroid nodule | <radiology> Hot on Tc-99m pertechnetate, cold on I-123 or I-131, indicates trapping, but no organification, same work-up as cold nodule (12 Dec 1998) |
| Arantius' nodule | A nodule at the centre of the free border of each semilunar valve at the beginning of the pulmonary artery and aorta. Synonym: nodulus valvulae semilunaris, Arantius' nodule, Bianchi's nodule, corpus arantii, Morgagni's nodule. (05 Mar 2000) |
| Bianchi's nodule | A nodule at the centre of the free border of each semilunar valve at the beginning of the pulmonary artery and aorta. Synonym: nodulus valvulae semilunaris, Arantius' nodule, Bianchi's nodule, corpus arantii, Morgagni's nodule. (05 Mar 2000) |
| recombination nodule | <molecular biology> Protein containing assemblies of about 90 nm diameter placed at intervals in the synaptonemal complexes that develop between homologous chromosomes at the zygotene stage of meiosis. Some nodules may be associated with the site of recombination. (18 Nov 1997) |
| rheumatic nodule | A small round or oval, mostly subcutaneous nodule made up chiefly of a mass of aschoff bodies and seen in cases of rheumatic fever. It is differentiated from the rheumatoid nodule which appears in rheumatoid arthritis, most frequently over bony prominences. (12 Dec 1998) |
| rheumatoid nodule | Subcutaneous nodules seen in 20-30% of rheumatoid arthritis patients. They may arise anywhere on the body, but are most frequently found over the bony prominences. The nodules are characterised histologically by dense areas of fibrinoid necrosis with basophilic streaks and granules, surrounded by a palisade of cells, mainly fibroblasts and histiocytes. (12 Dec 1998) |
| root nodule | <plant biology> Globular structure formed on the roots of certain plants, notably legumes and alder, by symbiotic association between the plant and a nitrogen fixing microorganism (Rhizobium in the case of legumes and Frankia in the case of alder and a variety of other plants). (18 Nov 1997) |
| milker's nodule virus | A virus in the family Poxviridae. (05 Mar 2000) |
| cold nodule | A thyroid nodule with a much lower uptake of radioactive iodine than the surrounding parenchyma; about one in four prove to be malignant. (05 Mar 2000) |
| Morgagni's nodule | A nodule at the centre of the free border of each semilunar valve at the beginning of the pulmonary artery and aorta. Synonym: nodulus valvulae semilunaris, Arantius' nodule, Bianchi's nodule, corpus arantii, Morgagni's nodule. (05 Mar 2000) |
| primary nodule | A lymphatic nodule having small lymphocytes and lacking a germinal centre. (05 Mar 2000) |
| Sakurai-Lisch nodule | Iris hamartomas typically seen in type 1 neurofibromatosis. Synonym: Sakurai-Lisch nodule. (05 Mar 2000) |
| Schmorl's nodule | Prolapse of the nucleus pulposus through the vertebral body endplate into the spongiosa of the vertebra. (05 Mar 2000) |