| TMP | thiamine monophosphate; thymidine monophosphate; thymidine-5'-monophosphate; thymolphthalein monopho... |
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| HAT | Halsted Aphasia Test; head, arm, trunk; heparin-associated thrombocytopenia; heterophil antibody tit... |
| dAMP | deoxyadenosine monophosphate; deoxyadenylate adenosine monophosphate |
| GMP | glucose monophosphate; good manufacturing practice; granule membrane protein; guanosine monophosphat... |
| TFT | Tri-Fluoro-Thymidine |
| dTMP | 2'-deoxy thymidine 5'-monophosphate |
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| TMP | Thymidine monophosphate |
| dThd | 2'-deoxy-thymidine |
| TK | 2-thymidine kinase |
| AZT | 3'-azido-3'-thymidine |
| thymidine 5'-monophosphate | A major constituent of DNA. Synonym: thymidine 5'-monophosphate, thymine nucleotide. (05 Mar 2000) |
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| thymidine monophosphate | <chemical> 5-thymidylic acid. A thymine nucleotide containing one phosphate group esterified to the deoxyribose moiety. Chemical name: 5'-Thymidylic acid (12 Dec 1998) |
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| ADP - thymidine kinase | <enzyme> Induced by herpes simplex virus infection of mouse fibroblasts Registry number: EC 2.7.1.118 Synonym: ADP-thymidine 5'-phosphotransferase (26 Jun 1999) |
| double thymidine block | <cell culture, procedure> A lab technique used to synchronise the cell cycles of all the cells in a culture. This is done by adding excessive amounts of thymidine (a deoxynucleoside) to the culture so that DNA replication is blocked. Eventually, all of the cells will reach the same point in the cell cycle and stop. (09 Oct 1997) |
| thymidine | <biochemistry> Term that is always used in practice for the nucleoside thymine deoxyriboside, not the riboside which naming of the other nucleosides might lead one to expect. (18 Nov 1997) |
| thymidine 5'-diphosphate | Thymidine esterified at its 5' position with diphosphoric acid. Acronym: dTDP (05 Mar 2000) |
| thymidine 5'-triphosphate | Thymidine esterified at its 5' position with triphosphoric acid; the immediate precursor of thymidylic acid in DNA. Acronym: dTTP (05 Mar 2000) |
| thymidine-diphospho-4-keto-6-deoxyglucose epimerase | <enzyme> Isolated from saccharopolyspora erythraea; catalyses the formation of tdp-4-keto-l-rhamnose from thymidine-diphospho-4-keto-6-deoxy-d-glucose Registry number: EC 5.1.3.- Synonym: tdkd-glucose epimerase, tdp-4-keto-6-deoxyglucose 3,5-epimerase, kde gene product (26 Jun 1999) |
| thymidine kinase | <enzyme> Of pyrimidine salvage, catalysing phosphorylation of thymine deoxyriboside to form its 5' phosphate, the nucleotide thymidylate. Animal cells lacking this enzyme can be selected by lethal synthesis, for example by resistance to bromodeoxyuridine and can be used as parentals in somatic hybridisation, since they are unable to grow in HAT medium. (18 Nov 1997) |
| thymidine permease | <chemical> (26 Jun 1999) |
| thymidine phosphorylase | <enzyme> The enzyme catalyzing the transfer of 2-deoxy-d-ribose from thymidine to orthophosphate, thereby liberating thymidine. Chemical name: Thymidine:orthophosphate deoxy-D-ribosyltransferase Registry number: EC 2.4.2.4 (12 Dec 1998) |
| thymidine triphosphate | A molecule which consists of the nitrogenous base thymine linked to the sugar ribose and which has a chain of three phosphate groups attached to the ribose in a linear fashion. TTP is required for DNA and RNA synthesis since it is a direct precursor molecule. (09 Oct 1997) |
| tritiated thymidine | Thymidine containing the hydrogen radionuclide, tritium (H); used as a marker to measure and localise by radioautography the synthesis of DNA, into which it is incorporated. (05 Mar 2000) |
| adenosine 3',5'-cyclic monophosphate | An activator of phosphorylase kinase and an effector of other enzymes, formed in muscle from ATP by adenylate cyclase and broken down to 5'-AMP by a phosphodiesterase; sometimes referred to as the "second messenger." A related compound (2',3') is also known. Synonym: cyclic adenylic acid, cyclic AMP, cyclic phosphate. Acronym: cAMP (05 Mar 2000) |
| adenosine monophosphate | <chemical> Adenylic acid. Adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. Chemical name: 5'-Adenylic acid (12 Dec 1998) |
| pentose monophosphate shunt | <biochemistry> A pathway of hexose oxidation in which glucose-6-phosphate undergoes two successive oxidations by NADP, the final one being an oxidative decarboxylation to form a pentose phosphate. Diverges from this when glucose-6-phosphate is oxidized to ribose 5 phosphate by the enzyme glucose-6 phosphate dehydrogenase. This step reduces NADP to NADPH, generating a source of reducing power in cells for use in reductive biosyntheses. In plants, part of the pathway functions in the formation of hexoses from carbon dioxide in photosynthesis. Also important as source of pentoses, for example for nucleic acid biosynthesis. This pathway is the main metabolic pathway in neutrophils, congenital deficiency in the pathway produces sensitivity to infection. Alternative metabolic route to Embden Meyerhof pathway for breakdown of glucose. (18 Nov 1997) |
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