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thiorphan <chemical> (+-)-n-(2-(mercaptomethyl)-1-oxo-3-phenylpropyl)glycine. A potent inhibitor of membrane metalloendopeptidase (enkephalinase). Thiorphan potentiates morphine-induced analgesia and attenuates naloxone-precipitated withdrawal symptoms.
Pharmacological action: protease inhibitors.
Chemical name: Glycine, N-(2-(mercaptomethyl)-1-oxo-3-phenylpropyl)-, (+-)-
(12 Dec 1998)
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