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acetoacetyl-succinic thiophorase <enzyme> An enzyme catalyzing the reversible conversion of acetoacetyl-CoA and succinate into succinyl-CoA and acetoacetate; malonyl-CoA can substitute for succinyl-CoA and a few other 3-oxo acids for the acetoacetate; an important step in order for the ketone bodies to serve as a fuel for extrahepatic tissues.
Synonym: 3-ketoacid-CoA transferase, acetoacetyl-succinic thiophorase.
(05 Mar 2000)
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