| thiolase | An acetyltransferase forming acetoacetyl-CoA from two molecules of acetyl-CoA, releasing one CoA. A key step in ketogenesis and sterol synthesis. Synonym: acetoacetyl-CoA thiolase, acetyl-CoA thiolase, thiolase. (05 Mar 2000) |
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| acetoacetyl-CoA thiolase | An acetyltransferase forming acetoacetyl-CoA from two molecules of acetyl-CoA, releasing one CoA. A key step in ketogenesis and sterol synthesis. Synonym: acetoacetyl-CoA thiolase, acetyl-CoA thiolase, thiolase. (05 Mar 2000) |
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| acetyl-CoA thiolase | An acetyltransferase forming acetoacetyl-CoA from two molecules of acetyl-CoA, releasing one CoA. A key step in ketogenesis and sterol synthesis. Synonym: acetoacetyl-CoA thiolase, acetyl-CoA thiolase, thiolase. (05 Mar 2000) |
| beta-ketoadipyl-coenzyme A thiolase | <enzyme> Last enzyme in the beta-ketoadipate pathway in pseudomonas putida; genbank l33795 Registry number: EC 2.3.1.- Synonym: pcaf gene product, beta-ketoadipyl-CoA thiolase (26 Jun 1999) |
| 2-methylacetoacetyl-CoA thiolase | <enzyme> An enzyme that is part of the l-isoleucine degradation pathway; it catalyses the conversion of 2-methylacetoacetyl-CoA (CH3COCH(CH3)COSCoA) to acetyl-CoA and propionyl-CoA. A deficiency of this enzyme leads to an accumulation of 2-methylacetoacetyl-CoA, causing episodes of severe metabolic acidosis and ketosis. (05 Mar 2000) |
| 3-ketoacyl-CoA thiolase | <enzyme> An enzyme catalyzing the thioclastic cleavage by coenzyme A of beta-ketoacyl-CoA, forming an acyl-CoA with a carbon chain shorter by two atoms, the missing two atoms appearing as acetyl-CoA. A step in fatty acid degradation. See: acetyl-CoA acetyltransferase. Synonym: 3-ketoacyl-CoA thiolase, beta-ketothiolase. (05 Mar 2000) |