| thienamycin | The first member of a family of des-thia-carbapenem nucleus antibiotics having a thioethylamine side-chain on the enamine portion of the fused 5-membered ring. (05 Mar 2000) |
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| thienamycin cyclase | <enzyme> Isolated from streptomyces lividans Registry number: EC 5.- (26 Jun 1999) |
| thienamycins | Beta-lactam antibiotics that differ from penicillins in having the thiazolidine sulfur atom replaced by carbon, the sulfur then becoming the first atom in the side chain. They are unstable chemically, but have a very broad antibacterial spectrum. Thienamycin and its more stable derivatives are proposed for use in combinations with enzyme inhibitors. (12 Dec 1998) |