| tetramethyl acridine | <chemical, molecular biology> 3, 6-bis(dimethylamino)acridinium chloride. A toxic, fluorescing dye that stains DNA and RNA and is typically used to identify cancerous tumour cells. When it binds to double-stranded DNA, it fluoresces green, when it binds with the phosphate groups of single-stranded DNA or RNA, it fluoresces orange. The chemical also causes frameshift mutations. (12 Mar 1998) |
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| acridine | 10-azaanthracene;a dye, dye intermediate, and antiseptic precursor (9-aminoacridine, acriflavine, proflavine hemisulfate derived from coal tar and irritating to skin and mucous membranes. Synonym: dibenzopyridine. (05 Mar 2000) |
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| acridine dyes | Derivatives of the compound acridine which is closely related to xanthene; important as fluorochromes in histology, cytochemistry, and chemotherapy; examples include acriflavine, acridine orange, and quinacrine mustard. (05 Mar 2000) |
| acridine orange | <chemical, molecular biology> 3, 6-bis(dimethylamino)acridinium chloride. A toxic, fluorescing dye that stains DNA and RNA and is typically used to identify cancerous tumour cells. When it binds to double-stranded DNA, it fluoresces green, when it binds with the phosphate groups of single-stranded DNA or RNA, it fluoresces orange. The chemical also causes frameshift mutations. (12 Mar 1998) |
| acridine yellow | A faintly yellow solution with strong bluish-violet fluorescence; used as a topical antiseptic and as a fluorescent stain in histology. Synonym: 5-aminoacridine hydrochloride, 9-aminoacridine hydrochloride. (05 Mar 2000) |