| tetracycline resistance | Nonsusceptibility of a microbe (usually a bacterium) to the action of tetracycline, which binds to the 30s ribosomal subunit and prevents the normal binding of aminoacyl-trna. (12 Dec 1998) |
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| antibiotics, tetracycline | <chemical> Broad-spectrum natural and semisynthetic antibiotics with a naphthacene structure obtained from various streptomyces species. Pharmacological action: protein synthesis inhibitor. (12 Dec 1998) |
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| tetracycline | <drug> Broad spectrum antibiotic that blocks binding of aminoacyl tRNA to the ribosomes of both gram-positive and gram-negative organisms (and those of organelles). Produced by Streptomyces aureofasciens. Other exaples include tetracycline, demeclocycline and doxycycline. (09 Oct 1997) |
| tetracycline 5a(11a)dehydrogenase | <enzyme> Catalyses the oxidation of 7-chloro-5a(11a)-dehydrotetracycline to 7-chlorotetracycline; uses nadp Registry number: EC 1.3.1.- (26 Jun 1999) |
| airway resistance | The opposition of the tracheobronchial tree to air flow: the mouth-to-alveoli pressure difference divided by the air flow. (12 Dec 1998) |
| ampicillin resistance | Nonsusceptibility of a microbe to the action of ampicillin, a penicillin derivative that interferes with cell wall synthesis. (12 Dec 1998) |
| androgen resistance syndromes | A class of disorders associated with 5a-steroid reductase deficiency, testicular feminization, and related disorders. Compare: steroid 5a-reductase, Reifenstein's syndrome, infertile male syndrome, testicular feminization syndrome. (05 Mar 2000) |
| antibiotic resistance | The ability of a bacterium tosynthesise a protein that neutralises an antibiotic. (09 Oct 1997) |
| antibiotic resistance gene | Genes in a microorganism which confer resistance to antibiotics, for example by coding for enzymes which destroy it, by coding for surface proteins which prevent it from entering the microorganism, or by being a mutant form of the antibiotic's target so that it can ignore it. (09 Oct 1997) |
| bacteriophage resistance | Resistance of a bacterial mutant to infection by a bacteriophage to which the parent (wild type) strain is susceptible. (05 Mar 2000) |
| beta-lactam resistance | Nonsusceptibility of an organism to the action of the beta-lactam antibiotics. (12 Dec 1998) |
| capillary resistance | The resistance offered to the flow of blood through the capillary portion of the peripheral vascular bed. (12 Dec 1998) |
| capillary resistance test | A tourniquet test used to determine presence of vitamin C deficiency or thrombocytopenia; a circle 2.5 cm in diameter, the upper edge of which is 4 cm below the crease of the elbow, is drawn on the inner aspect of the forearm, pressure midway between the systolic and diastolic blood pressure is applied above the elbow for 15 minutes, and a count of petechiae within the circle is made: 10, normal; 10 to 20, marginal zone; over 20, abnormal. See: Rumpel-Leede test. Synonym: capillary resistance test, vitamin C test. (05 Mar 2000) |
| vascular resistance | An expression of the resistance offered by the systemic arterioles, and to a lesser extent by the capillaries, to the flow of blood. (12 Dec 1998) |
| resistance | The failure of a condition to respond or remit following treatment. (16 Dec 1997) |
| resistance, antibiotic | The ability of bacteria and other microorganisms to withstand an antibiotic to which they were once sensitive (and were once stalled or killed outright). Also called drug resistance. (12 Dec 1998) |