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anti-inflammatory agent, topical Anti-inflammatory agent that are applied to the skin and whose pharmacological effect only occurs at the area of application.
(12 Dec 1998)
glucocorticoids, topical A class of corticosteroids that produces suppression of inflammatory diseases when applied as ointments, lotions, or other topical dosage forms. Penetration of the preparations may be increased by means of occlusive dressings.
(12 Dec 1998)
prednisolone, topical Prednisolone that is applied topically as an anti-inflammatory agent.
(12 Dec 1998)
hydrocortisone, topical Hydrocortisone that is applied topically as an anti-inflammatory agent.
(12 Dec 1998)
topical <pharmacology> Pertaining to a particular surface area, as a topical anti-infective applied to a certain area of the skin and affecting only the area to which it is applied.
Origin: Gr. Topikos
(18 Nov 1997)
topical anaesthesia Superficial loss of sensation in conjunctiva, mucous membranes or skin, produced by direct application of local anaesthetic solutions, ointments, or jellies.
(05 Mar 2000)
topical anaesthetic An anaesthetic that is applied or sprayed on the surface of the skin (or mucous membranes) for providing pain relief. Commonly used are benzocaine, butacaine, cyclomethycaine, lidocaine, tetracaine and dibucaine.
(27 Sep 1997)
topical antibiotics A ointment (or cream) based medication that kills bacteria.
Examples include Neosporin, Bactroban, Garamycin, bacitracin, gentamicin, mupirocin, neomycin, silver sulphasalazine, chloramphenicol and clindamycin.
(27 Sep 1997)
topical chemotherapy Treatment with anticancer drugs in a lotion or cream.
(12 Dec 1998)
fluorides, topical Fluorides, usually as pastes or gels, used for topical application to reduce the incidence of dental caries.
(12 Dec 1998)
testosterone <hormone> Male sex hormone (androgen) secreted by the interstitial cells of the testis of mammals and responsible for triggering the development of sperm and of many secondary sexual characteristics.
(18 Nov 1997)
testosterone 15-alpha hydroxylase <enzyme> A haem-thiolate protein (cytochrome p-450)
Registry number: EC 1.14.15.-
Synonym: cytochrome p-450(15alpha), testosterone 15-alpha monooxygenase, steroid 15-alpha-hydroxylase, cytochrome p-4502a-4, cyp2a-4, cyp2a4
(26 Jun 1999)
testosterone 16 beta-hydroxylase <enzyme> See also record for testosterone hydroxylase
Registry number: EC 1.14.99.-
Synonym: ttt 16 beta-hydroxylase
(26 Jun 1999)
testosterone 17 beta-dehydrogenase <enzyme> Catalyses reversibly the oxidation of testosterone to 4-androstene-3,17-dione in the presence of nad; was mapped to testosterone dehydrogenases (81-93) (see under 17-hydroxysteroid dehydrogenases (81-90); on-line search 17-hydroxysteroid dehydrogenases (81-93), index medicus see testosterone dehydrogenases (91-93) and 17-hydroxysteroid dehydrogenases (81-90)
Registry number: EC 1.1.1.63
Synonym: 17 beta-hydroxysteroid-nad+ 17-oxidoreductase
(26 Jun 1999)
testosterone 2alpha-hydroxylase <enzyme> From mouse liver, member of the murine cytochrome p450 2d family; amino-terminal amino acid sequence given in first source
Registry number: EC 1.14.99.-
Synonym: cytochrome p450 2alpha, cytochrome p-450 2alpha, androstenedione 2alpha-hydroxylase, androgen 2alpha-hydroxylase
(26 Jun 1999)
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