| peptide chain termination | The process whereby the last amino acid is added to a polypeptide. This termination is signaled by one of three termination triplets in the mRNA, immediately following the last amino acid codon. (12 Dec 1998) |
|---|---|
| peptide termination factors | Proteins that are exclusively involved in the termination reactions of protein synthesis on the ribosome. (12 Dec 1998) |
| termination | <molecular biology> Stop of mRNA synthesis (i.e., transcription) at the terminator site Top of protein synthesis (i.e., translation) at the stop codon. (09 Oct 1997) |
| termination codon | <molecular biology> The three codons, UAA known as ochre, UAG as amber and UGA as opal, that do not code for an amino acid but act as signals for the termination of protein synthesis. They are not represented by any tRNA and termination is catalysed by protein release factors. There are two release factors in E. Coli, RF1 recognises UAA and UAG, RF2 recognises UAA and UGA. Eukaryotes have a single GTP requiring factor, eRF. See: ochre suppressor, amber suppressor. (13 Jan 1998) |
| termination factor | <molecular biology> Any of several proteins in the cytosol that cut a completed polypeptide loose from a ribosome. (13 Jan 1998) |
| termination region | <molecular biology> A DNA sequence that signals the end of transcription. (13 Jan 1998) |
| termination sequence | <molecular biology> The three codons, UAA known as ochre, UAG as amber and UGA as opal, that do not code for an amino acid but act as signals for the termination of protein synthesis. They are not represented by any tRNA and termination is catalysed by protein release factors. There are two release factors in E. Coli, RF1 recognises UAA and UAG, RF2 recognises UAA and UGA. Eukaryotes have a single GTP requiring factor, eRF. See: ochre suppressor, amber suppressor. (13 Jan 1998) |
| acoustic tolerance | The maximum sound pressure level that can be experienced without producing pain or permanent defect of hearing in a normal individual. (05 Mar 2000) |
| bile acid tolerance test | A sensitive test of hepatic dysfunction; following oral administration of labelled or unlabelled bile acid, the measured fractional disappearance rate or 10-minute retention is measured. (05 Mar 2000) |
| galactose tolerance test | A liver function test, based on the ability of the liver to convert galactose to glycogen, measured by the rate of excretion of galactose following ingestion or intravenous injection of a known amount; normally, less than 3 g appear in the urine within 5 hours after the ingestion of 40 g. (05 Mar 2000) |
| radiation tolerance | The ability of some cells or tissues to withstand ionizing radiation without serious injury. Tolerance depends on the species, cell type, and physical and chemical variables, including radiation-protective agents and radiation-sensitizing agents. (12 Dec 1998) |
| pain tolerance | The greatest intensity of painful stimulation that an individual is able to tolerate. (05 Mar 2000) |
| gamma-tolerance | The tolerance of a person or a piece of equipment to forces that develop as a result of acceleration or deceleration. (05 Mar 2000) |
| vibration tolerance | The maximum vibratory or oscillatory movements that an individual can experience and bear without pain; the limit of tolerance is a function of amplitude and frequency of the vibration and varies with the direction of application. (05 Mar 2000) |
| glucose tolerance factor | A water-soluble complex containing chromium needed for normal glucose tolerance. (05 Mar 2000) |