teni : KMLE 의학 검색 엔진 - 의학사전, 의학용어, 의학약어, 의학논문, 약품/의약품 검색

MeSH(Medical Subject Headings) 맞춤 검색 (http://www.nlm.nih.gov) 결과 : 1 페이지: 1

Teniposide - 새창 A semisynthetic derivative of PODOPHYLLOTOXIN that exhibits antitumor activity. Teniposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent cells from entering into the mitotic phase of the cell cycle, and lead to cell death. Teniposide acts primarily in the G2 and S phases of the cycle.
Synonyms : Bristol-Myers Brand of Teniposide, Bristol-Myers Squibb Brand of Teniposide, NSC-122819, Teniposide, (5a alpha, 9 alpha(S*))-Isomer, VM-26, Vumon, Bristol Myers Brand of Teniposide, Bristol Myers Squibb Brand of Teniposide, NSC 122819, NSC122819, VM 26, VM26