| vasculitis | <pathology> Inflammation of a vessel, angiitis. Origin: L. Vasculum = vessel (18 Nov 1997) |
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| vasculitis, allergic cutaneous | Vasculitis due to allergic reaction, marked by such cutaneous lesions as papules, macules, vesicles, urticarial wheals, purpura, and small ulcers, and accompanied by itching and usually a slight fever and malaise. (12 Dec 1998) |
| vasculitis, hypersensitivity | Heterogeneous group of disorders characterised by a vasculitic syndrome presumed to be associated with a hypersensitivity reaction following exposure to an antigen such as an infectious agent, a drug, or other foreign or endogenous substance. (12 Dec 1998) |
| cutaneous vasculitis | An acute form of vasculitis which may affect the skin only, but also may involve other organs, with a polymorphonuclear infiltrate in the walls of and surrounding small (dermal) vessels. Nuclear fragments are formed by karyorrhexis of the neutrophils. See: leukocytoclastic vasculitis. Synonym: allergic angiitis, hypersensitivity vasculitis. (05 Mar 2000) |
| hypersensitivity vasculitis | An acute form of vasculitis which may affect the skin only, but also may involve other organs, with a polymorphonuclear infiltrate in the walls of and surrounding small (dermal) vessels. Nuclear fragments are formed by karyorrhexis of the neutrophils. See: leukocytoclastic vasculitis. Synonym: allergic angiitis, hypersensitivity vasculitis. (05 Mar 2000) |
| hypocomplementemic vasculitis | Cutaneous lesions resembling urticaria but lasting more than 24 hours, with biopsy findings of leukocytoclastic vasculitis and variable systemic changes, usually with hypocomplementemia. Synonym: hypocomplementemic vasculitis. (05 Mar 2000) |
| nodular vasculitis | Chronic or recurrent nodular lesions of subcutaneous tissue, especially of the legs of older women, with lobular panniculitis, granulomatous inflammation with multinucleated giant cells, focal necrosis, and obliterative inflammation of the small blood vessels, resembling erythema induratum but without evidence of associated tuberculosis. (05 Mar 2000) |
| urticarial vasculitis | Cutaneous lesions resembling urticaria but lasting more than 24 hours, with biopsy findings of leukocytoclastic vasculitis and variable systemic changes, usually with hypocomplementemia. Synonym: hypocomplementemic vasculitis. (05 Mar 2000) |
| leukocytoclastic vasculitis | Cutaneous acute vasculitis characterised clinically by palpable purpura, especially of the legs, and histologically by exudation of the neutrophils and sometimes fibrin around dermal venules, with nuclear dust and extravasation of red cells; may be limited to the skin or involve other tissues as in Henoch-Schonlein purpura. See: cutaneous vasculitis. Origin: G. Leukos, white, + kytos, cell, + klastos, broken, fr. Klao, to break (05 Mar 2000) |
| livedo vasculitis | Hyaline degeneration of the walls of small dermal blood vessels with occlusion seen with cryoglobulinaemia or in atrophie blanche. (05 Mar 2000) |
| rheumatoid arthritis, systemic-onset juvenile | Also known as systemic-onset juvenile chronic arthritis. Still's disease presents with systemic (bodywide) illness including high intermittent fever, a salmon-coloured skin rash, swollen lymph glands, enlargement of the liver and spleen, and inflammation of the lungs (pleuritis) and around the heart (pericarditis). The arthritis may not be immediately apparent but it does appear and may persist after the systemic symptoms are gone. (12 Dec 1998) |
| portal-systemic anastomoses | Naturally-occurring venous communications between tributaries of the portal venous system and tributaries of the systemic venous system. The major portal-systemic anastomoses include: 1) oesophageal branches of left gastric vein with oesophageal veins, 2) superior rectal vein with middle and inferior rectal veins, 3) paraumbilical veins with subcutaneous veins of anterior abdominal wall, 4) retroperitoneal veins with venous branches of veins of the colon and bare area of the liver, and 5) a patent ductus venosus connecting left branch of portal vein to inferior vena cava (rare). These anastomoses are important clinically, providing collateral circulation during portal obstruction or hypertension, at which time they may become varicose. See: caput medusae, oesophageal varices, haemorrhoids. Surgically-created communications between the portal vein and the inferior vena cava or their tributaries, to relieve portal hypertension. Synonym: portacaval anastomoses. (05 Mar 2000) |
| portal-systemic encephalopathy | An encephalopathy associated with cirrhosis of the liver, attributed to the passage of toxic nitrogenous substances from the portal to the systemic circulation; cerebral manifestations may include coma. Synonym: hepatic encephalopathy. (05 Mar 2000) |
| scleroderma, systemic | A chronic, progressive dermatosis characterised by boardlike hardening and immobility of the affected skin, with visceral involvement, especially of lungs, oesophagus, kidneys and heart. It may be accompanied by calcinosis, raynaud's phenomenon, and telangiectasis (crest syndrome). It includes acrosclerosis and sclerodactyly. (12 Dec 1998) |
| systemic | <anatomy> Pertaining to or affecting the body as a whole. (18 Nov 1997) |