| linker | A short, double-stranded oligonucleotide containing a restriction endonuclease recognition site, which is ligated to the ends of a DNA fragment. (04 Jul 1999) |
|---|---|
| linker DNA | The DNA found between nucleosomes on chromatin; since it is not complexed to proteins as strongly as other forms of DNA, it is accessible to exonuclease hydrolysis. (05 Mar 2000) |
| linker scanning | A type of deletion mutagenesis where the distance and/or reading frame between potentially important regions is maintained by replacement with a synthetic oligonucleotide of known sequence. (05 Mar 2000) |
| androgens, synthetic | Compounds obtained by chemical synthesis which possess masculinizing activities, but differ in structure from naturally occurring androgens. (12 Dec 1998) |
| vaccines, synthetic | Small synthetic peptides that mimic surface antigens of pathogens and are immunogenic, or vaccines manufactured with the aid of recombinant DNA techniques. The latter vaccines may also be whole viruses whose nucleic acids have been modified. (12 Dec 1998) |
| genes, synthetic | Biologically functional sequences of DNA chemically synthesised in vitro. (12 Dec 1998) |
| glucocorticoids, synthetic | <chemical> Synthetic chemical compounds which increase gluconeogenesis, raising the concentration of liver glycogen and blood sugar, but differ in structure from naturally occurring glucocorticoids. Pharmacological action: steroidal anti-inflammatory agents, topical anti-inflammatory agents. (12 Dec 1998) |
| resins, synthetic | Polymers of high molecular weight which at some stage are capable of being molded and then harden to form useful components. (12 Dec 1998) |
| mineralocorticoids, synthetic | Synthetic steroids that mimic the activity of the mineralocorticoids obtained from the adrenal cortex, but differ in structure from the naturally occurring mineralocorticoids. (12 Dec 1998) |
| contraceptives, oral, synthetic | Oral contraceptives which owe their effectiveness to synthetic preparations. (12 Dec 1998) |
| contraceptives, postcoital, synthetic | Postcoital contraceptives which owe their effectiveness to synthetic preparations. (12 Dec 1998) |
| progestational hormones, synthetic | Compounds obtained by chemical synthesis that possess progestational activity, but differ in structure from naturally occurring progestational hormones. (12 Dec 1998) |
| prostaglandin endoperoxides, synthetic | Synthetic compounds that are analogs of the naturally occurring prostaglandin endoperoxides and that mimic their pharmacologic and physiologic activities. They are usually more stable than the naturally occurring compounds. (12 Dec 1998) |
| prostaglandins a, synthetic | Analogs or derivatives of prostaglandin a that do not occur naturally in the body. They do not include the product of the chemical synthesis of hormonal pga. (12 Dec 1998) |
| prostaglandins e, synthetic | Analogs or derivatives of prostaglandins e that do not occur naturally in the body. They do not include the product of the chemical synthesis of hormonal pge. (12 Dec 1998) |