| superoxide | <chemistry> Term used interchangeably for the superoxide anion or the weak acid HO2(.). Superoxide is generated both by prokaryotes and eukaryotes and is an important product of the metabolic burst of neutrophil leucocytes. A very active oxygen species, it can cause substantial damage and may be responsible for the inactivation of plasma antiproteases that contributes to the pathogenesis of emphysema. (18 Nov 1997) |
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| superoxide anion | <chemistry> A harmful derivative of oxygen capable of oxidative destruction of cell components. (09 Oct 1997) |
| superoxide dismutase | <enzyme> Any of a range of metalloenzymes that catalyses the formation of hydrogen peroxide and oxygen from superoxide and thus protects against superoxide induced damage. Usually has either iron or manganese as the metal cation in prokaryotes, copper or zinc in eukaryotes. (18 Nov 1997) |
| superoxides | <chemical> Highly reactive compounds produced when oxygen is reduced by a single electron. In biological systems, they may be generated during the normal catalytic function of a number of enzymes and during the oxidation of haemoglobin to methemoglobin. In living organisms, superoxide dismutase protects the cell from the deleterious effects of superoxide. Chemical name: Superoxide (12 Dec 1998) |
| monomethoxypolyethylene glycol-superoxide dismutase | <chemical> Pharmacological action: free radical scavengers Synonym: mpeg-sod (26 Jun 1999) |
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| polyethylene glycol-superoxide dismutase | <chemical> A free radical scavenger Pharmacological action: free radical scavengers Synonym: peg-sod (26 Jun 1999) |
| polyhemoglobin-superoxide dismutase-catalase | <chemical> Intermolecularly cross-linked haemoglobin, superoxide dismutase and catalase; prevents methemoglobin formation and iron release Pharmacological action: free radical scavengers Synonym: polyhb-sod-catalase (26 Jun 1999) |
| polyoxyethylene-superoxide dismutase | <chemical> Recombinant human cu,zn superoxide dismutase with polyoxyethylene; decreases side effects of superoxide-generating antineoplastics such as adriamycin and mitomycin c Synonym: sod-poe, poe-sod, polyoxyethylene-modified superoxide dismutase (26 Jun 1999) |
| zinc superoxide | ZnO2;a yellowish white powder, insoluble in water and decomposed by acids; used in pharmaceutical preparations. Synonym: zinc superoxide. (05 Mar 2000) |