| succinic acid | <chemical> A water-soluble, colourless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. Pharmacological action: anti-ulcer agents, radiation-protective agents. (12 Dec 1998) |
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| succinic acid cycle | A series of oxidation reduction reactions in which succinic acid and other 4-carbon atoms acids (fumaric, malic, oxaloacetic) take part in the oxidation of pyruvic acid as part of the tricarboxylic acid cycle. See: dicarboxylic acid cycle. (05 Mar 2000) |
| succinic acids | A class of dicarboxylic acids with the general structure of butanedioic acid (succinic acid). They are used in perfumery and as a chemical intermediate in medicine. (12 Dec 1998) |
| alpha-hydroxymethyl-alpha'-(N-acetylaminomethylene)succinic acid hydrolase | <enzyme> Involved in degradation of vitamin b6; forms acetic acid plus ammonia plus carbon dioxide plus alpha-hydroxymethyl-succinic monoaldehyde Registry number: EC 3.5.1.- Synonym: compound b hydrolase (26 Jun 1999) |
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| alpha-(N-acetylaminomethylene)succinic acid hydrolase | <enzyme> Involved in degradation of vitamin b6; forms acetic acid plus ammonia plus carbon dioxide plus succinic monoaldehyde Registry number: EC 3.5.1.- Synonym: compound a hydrolase (26 Jun 1999) |
| acetoacetyl-succinic thiophorase | <enzyme> An enzyme catalyzing the reversible conversion of acetoacetyl-CoA and succinate into succinyl-CoA and acetoacetate; malonyl-CoA can substitute for succinyl-CoA and a few other 3-oxo acids for the acetoacetate; an important step in order for the ketone bodies to serve as a fuel for extrahepatic tissues. Synonym: 3-ketoacid-CoA transferase, acetoacetyl-succinic thiophorase. (05 Mar 2000) |
| succinic | <chemistry> Pertaining to, or derived from, amber; specif, designating a dibasic acid, CH.(COH), first obtained by the dry distillation of amber. It is found in a number of plants, as in lettuce and wormwood, and is also produced artificially as a white crystalline substance having a slightly acid taste. Origin: Cf. F. Succinique. See Succinate. Source: Websters Dictionary (01 Mar 1998) |
| succinic anhydrides | A subclass of anhydrides with the general structure of dihydrofurandione. They can be substituted on any carbon atom. They modify and inhibit proteins and enzymes and are used in the acylation of amino- and hydroxyl groups. (12 Dec 1998) |
| succinic thiokinase | A ligase reversibly reacting succinate and CoA with ATP to produce ADP, inorganic phosphate, and succinyl-CoA, a similar synthetase, but one able to use itaconate as well as succinate and GTP (or ITP) in place of ATP; a part of the tricarboxylic acid cycle. Synonym: succinic thiokinase, succinyl-CoA ligase. (05 Mar 2000) |
| Rambourg's chromic acid-phosphotungstic acid stain | <technique> A stain for glycoproteins, used with an electron microscope, with which ultrathin tissue sections reveal complex carbohydrates in the same locations as shown by Rambourg's periodic acid-chromic methenamine-silver stain. (05 Mar 2000) |
| a1-acid glycoprotein | <biology> Plasma protein of mammals and birds, 38% carbohydrate. In humans a single chain glycoprotein of 39 kD. Increased levels are associated with inflammation, pregnancy and various diseases. (18 Nov 1997) |
| abscisic acid | <biochemistry> A lipid hormone that inhibits cell growth in plants, it is associated with fruit drop, leaf death and seed dormancy. It is synthesised in the plastids from carotenoids. This hormone helps plants deal with water loss, and its effects can be reversed with gibberellins. (06 May 1997) |
| abscisic acid 8'-hydroxylase | <enzyme> Catalyses conversion of abscisic acid to 8'-hydroxyabscisic acid, which rearranges to phaseic acid Registry number: EC 1.14.99.- Synonym: aba 8'-hydroxylase (26 Jun 1999) |
| acetic acid | <chemical> The acid most commonly associated with vinegar, it is the most commercially important organic acid and is used to manufacture a wide range of chemical products, such as plastics and Acetobacter but, except for making vinegar, is usually made through synthetic processes. Derivatives of acetic acid which may be formed by substitution reactions. Mono- and di-substituted, as well as, halogenated compounds have been synthesised. Experimentally, alpha- and n2- substituted acetic acids have been examined for their anti-inflammatory activity and effect on the central nervous system respectively. Additionally, limited exposure data has been collected on dibromo and dichloroacetic acids to determine whether they pose health effects. Synonym: ethanoic acid. (26 Jun 1999) |
| acetoacetic acid | CH3COCH2COOH;one of the ketone bodies, formed in excess and appearing in the urine in starvation or diabetes. Synonym: diacetic acid. (05 Mar 2000) |
| acetohydroxamic acid | C2H5NO2; N-Hydroxyacetamide;an inhibitor of urease, used as adjunctive therapy in chronic urea-splitting urinary infections. (05 Mar 2000) |
| acetrizoic acid | <chemical> A water-soluble, iodinated radiographic contrast medium, used as sodium acetrizoate in hysterosalpingography. Pharmacological action: contrast media. Chemical name: Benzoic acid, 3-(acetylamino)-2,4,6-triiodo- (12 Dec 1998) |
| acetylsalicylic acid | <drug> An odourless, white, slightly bitter drug used to reduce pain, fever, inflammation and sometimes to prevent blood clotting. Also called aspirin. Some people cannot tolerate it because it can cause stomach bleeding, however. It is soluble in both water and alcoholand melts at 132 to 136 degrees C. (06 May 1997) |