| centromere | <cell biology> The region in eukaryote chromosomes where daughter chromatids are joined together. The kinetochore, to which the spindle chromosomes are attached, lies adjacent to the centromere. The centromeric DNA codes for the kinetochore. (18 Nov 1997) |
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| centromere banding stain | <technique> A selective chromosome banding stain used in human cytogenetics, employing Giemsa stain after most of the DNA is denatured or extracted by treatment with alkali, acid, salt, or heat; only heterochromatic regions close to the centromeres and rich in satellite DNA stain, with the exception of the Y chromosome whose long arm usually stains throughout. Synonym: centromere banding stain. (05 Mar 2000) |
| submetacentric | See: submetacentric chromosome. (05 Mar 2000) |
| submetacentric chromosome | A chromosome with the centromere so placed that it divides the chromosome into two arms of strikingly unequal length. (05 Mar 2000) |