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subacute necrotizing encephalomyelopathy an encephalopathy of unclear clinical and pathological criteria, causing neuropathologic damage like that of the Wernicke-Korsakoff syndrome. It occurs in two forms: The infantile form, which may be the same as pyruvate carboxylase deficiency, is characterized by degeneration of gray matter with necrosis and capillary proliferation in the brain stem; hypotonia, seizures, and dementia; anorexia and vomiting; slow or arrested development; and ocular and respiratory disorders. ...
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