| streptolysin O | Oxygen labile thiol activated haemolysin (68 kD). Haemolysis is inhibited by cholesterol and only cells with cholesterol in their membranes are susceptible. Toxin aggregates are linked to cholesterol to form a channel 30 nm diameter in the membrane and nonosmotic lysis follows. Markedly inhibits neutrophil movement and stimulates secretion, but has little effect on monocytes. (18 Nov 1997) |
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| anti-streptolysin O titres | <immunology, microbiology> A special serologic test, known as anti-streptolysin O, that measures the quantity of antibody to a component of streptococcal bacteria. A useful diagnostic test for scarlet fever, rheumatic fever and other streptococcal disease. (13 Jan 1998) |
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| streptolysin | A haemolysin produced by streptococci. (05 Mar 2000) |
| streptolysin S | Thought to be a peptide of 28 residues: causes zone of _ haemolysis around streptococcal colonies on blood agar. Mechanism of haemolysis unclear. Toxic to leucocytes, platelets and several cell lines. (18 Nov 1997) |