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acute post-streptococcal glomerulonephritis <nephrology> A disease of the kidneys that results in inflammation of the glomerulus (the portion of the kidney that filters the blood).
Conditions which may cause glomerulonephritis include post-streptococcal disease (strep throat), lupus, syphilis, bacterial endocarditis, membranoproliferative glomerulonephritis, sepsis, vasculitis, Goodpasture's syndrome, typhoid fever, Henoch-Schonlein purpura, hepatitis or a viral infection (for example mumps, measles, mononucleosis).
(27 Sep 1997)
group A streptococcal necrotizing fasciitis A complication of infection with GAS (group A streptococci) in which the bacteria attacks and destroys muscle tissue. According to the CDC, 5-10% of people with severe GAS infection develop necrotizing fasciitis. Though the infection can be treated with antibiotics, the fatality rate is close to 30%. This complication often develops as a wound infection after surgery or injury.
(05 Mar 2000)
streptococcal Relating to or caused by any organism of the genus Streptococcus.
(05 Mar 2000)
streptococcal fibrinolysin <enzyme> Plasminogen activator released by Streptococcus pyogenes. Occurs in two forms, A and B.
(18 Nov 1997)
streptococcal infections Infections with bacteria of the genus streptococcus.
(12 Dec 1998)
streptococcal lymphadenitis A contagious bacterial disease of pigs caused by a group E streptococcus and characterised by the formation of abscesses in the cervical and/or cephalic lymph nodes.
(05 Mar 2000)
streptococcal nuclease <enzyme> From streptococcus haemolyticus; degrades RNA and DNA producing oligonucleotides terminating in 5'-phosphate
Registry number: EC 3.1.30.-
(26 Jun 1999)
streptococcal pneumonia Pneumonia due to Streptococcus pyogenes.
(05 Mar 2000)
streptococcal toxins Group of haemolytic exotoxins released by Streptococci. _ haemolysin: 26-39 Kd (four types), forms ring like structures in membranes (see Streptolysin O). Lipid target unclear. _ haemolysin: a hot cold haemolysin with sphingomyelinase C activity. _ haemolysin: complex of two proteins (29 and 26 kD) that act synergistically, rabbit erythrocytes particularly sensitive. _ toxin: heat stable peptide (5 kD) with high proportion of hydrophobic amino acids. Seems to act in a detergent like manner (c.f. Subtilysin), but may form hydrophilic transmembrane pores by cooperative interaction with other _ toxin molecules. Leucocidin (Panton Valentine leucocidin): two components f (fast migration on CM cellulose column: 32 kD) and s (slow: 38 kD). Mode of action contentious.
See: Streptococcus, streptolysins O and S, erythrogenic toxin.
(18 Nov 1997)
acute necrotizing ulcerative gingivitis An acute or recurrent gingivitis of young and middle-aged adults characterised clinically by gingival erythema and pain, fetid odour, and necrosis and sloughing of interdental papillae and marginal gingiva which gives rise to a gray pseudomembrane; fever, regional lymphadenopathy, and other systemic manifestations also may be present. A fusiform bacillus and Treponema vincentii can be isolated from the gingival tissues in large numbers and are felt to play a significant but poorly defined role in the pathogenesis.
Synonym: fusospirochetal gingivitis, trench mouth, ulceromembranous gingivitis, Vincent's disease, Vincent's infection.
(05 Mar 2000)
atypical gingivitis Intense hyperaemic oedema and inflammation of the gingiva resulting from a hypersensitivity reaction. A dense plasma cell infiltrate is seen in the lamina propria.
Synonym: atypical gingivitis.
(05 Mar 2000)
marginal gingivitis Gingivitis in which the clinical alterations are confined to the marginal gingiva and do not involve the attached gingiva.
(05 Mar 2000)
gingivitis <pathology> Inflammation of the gingivae. Gingivitis associated with bony changes is referred to as periodontitis.
Synonym: oulitis, ulitis.
(18 Nov 1997)
gingivitis, necrotizing ulcerative An acute or chronic gingival infection characterised by redness and swelling, necrosis extending from the interdental papillae along the gingival margins, pain, haemorrhage, necrotic odour, and often a pseudomembrane. The condition may extend to the oral mucosa, tongue, palate, or pharynx.
(12 Dec 1998)
chronic desquamative gingivitis A clinical term for a gingival condition of unknown aetiology, usually encountered in middle-aged and older women, characterised by erythema, mucosal atrophy, and desquamation, and usually accompanied by a burning sensation and pain; diagnosis is usually made by biopsy and direct immunofluorescence.
Synonym: gingivosis.
(05 Mar 2000)
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