| Stevens-Johnson syndrome | <syndrome> This is a severe form of allergic reaction that most often results from a medication (for example penicillins). The rash can be generalised and even appear on the palms of the hands and soles of the feet. Stevens-Johnson syndrome is considered to be a variant of erythema multiforme that results in the formation of bullous (blebs) lesions on the soles of the feet, palms and inside the mouth. Stevens-Johnson syndrome may also occur in association with some viral infections and Mycoplasma infections. (27 Sep 1997) |
|---|---|
| Stevens | Albert M., U.S. Paediatrician, 1884-1945. See: Stevens-Johnson syndrome. (05 Mar 2000) |
| Dubin-Johnson syndrome | <syndrome> An inherited disorder (autosomal recessive) that is characterised by long-standing mild jaundice. This occurs secondary to an abnormality in the transport of bilirubin from the liver to the biliary system. This leads to an accumulation of bilirubin in the liver. Avoidance of alcohol and medications which can affect the liver is important. Inheritance: autosomal recessive. (27 Sep 1997) |
| mead-johnson nutritionals | A division of the Mead-Johnson Corporation and maker of Enfamil (R), ProSobee (R), Nutramigen (R), LactoFree (R) and other fine infant nutritional products. (27 Sep 1997) |
| Wheeler-Johnson test | Cystosine or uracil when treated with bromine yields dialuric acid which gives a green colour with excess of barium hydroxide. (05 Mar 2000) |
| Johnson, Frank | <person> U.S. Paediatrician, 1894-1934. See: Stevens-Johnson syndrome. (05 Mar 2000) |
| Johnson, Frank B | <person> U.S. Pathologist, *1919. See: Dubin-Johnson syndrome. (05 Mar 2000) |
| johnson grass | <botany> A tall perennial grass (Sorghum Halepense), valuable in the Southern and Western States for pasture and hay. The rootstocks are large and juicy and are eagerly sought by swine. Synonym: Cuba grass, Means grass, Evergreen millet, and Arabian millet. Origin: Named after W. Johnson of Alabama, who planted it about 1840-1845. Source: Websters Dictionary (01 Mar 1998) |
| Johnson, Harry | <person> U.S. Dentist. See: Johnson's method. (05 Mar 2000) |
| Johnson's method | A method of filling the root canals of teeth by dissolving gutta-percha cones in a chloroform-rosin medium within the root canal. Synonym: Callahan's method, Johnson's method. (05 Mar 2000) |
| Johnson, Treat Baldwin | <person> U.S. Chemist, 1875-1947. See: Wheeler-Johnson test. (05 Mar 2000) |
| Aarskog-Scott syndrome | A syndrome of ocular hypertelorism, anteverted nostrils, broad upper lip, saddle-bag scrotum, and laxity of ligaments resulting in genu recurvatum, flat feet, and hyperextensible fingers; X-linked and autosomal dominant forms. Synonym: Aarskog-Scott syndrome. (05 Mar 2000) |
| Aarskog syndrome | <syndrome> Grier et al. (1983) reported father and 2 sons with typical Aarskog syndrome, including short stature, hypertelorism, and shawl scrotum. They tabulated the findings in 82 previous cases. X-linked recessive inheritance has been repeatedly suggested. The family reported by Welch (1974) had affected males in 3 consecutive generations. Thus, there is either genetic heterogeneity or this is an autosomal dominant with strong sex-influence and possibly ascertainment bias resulting from use of the shawl scrotum as a main criterion. Stretchable skin was present in the cases of Grier et al. (1983). Teebi et al. (1993) reported the case of an affected mother and 4 sons (including a pair of monozygotic twins) by 2 different husbands. They suggested that the manifestations were as severe in the mother as in the sons and that this suggested autosomal dominant inheritance. Actually, the mother seemed less severely affected, compatible with X-linked inheritance. Clinical signs: Mild to moderate short stature,normocephaly, Widow's peak hair, maxillary hypoplasia, broad nasal bridge, anteverted nostrils, long philtrum, broad upper lip, curved linear dimple below the lower lip, hypertelorism, ptosis, down-slanted palpebral fissures, ophthalmoplegia, strabismus, hyperopic astigmatism, large cornea, floppy ears, lop-ears,cleft lip/palate, shawl scrotum, saddle-bag scrotum, cryptorchidism, brachydactyly, digital contractures, clinodactyly, mild syndactyly, transverse palmar crease, lymphoedema of the feet, ligamentous laxity, osteochondritis dissecans, proximal finger joint hyperextensibility, flexed distal finger joints, genu recurvatum, flat feet, stretchable skin, cervical spine hypermobility, odontoid anomaly, macrocytic anaemia, hemochromatosis, hepatomegaly, portal cirrhosis, imperforate anus, rectoperineal fistula, interstitial pulmonary disease, sternal deformity. Inheritance: Sex-influenced autosomal dominant form, also X-linked form. (05 Aug 1998) |
| abdominal muscle deficiency syndrome | <syndrome> Congenital absence (partial or complete) of abdominal muscles, in which the outline of the intestines is visible through the protruding abdominal wall; in males, genitourinary anomalies (urinary tract dilation and cryptorchidism) are also found; genetics unclear. (05 Mar 2000) |
| abstinence syndrome | <syndrome> A constellation of physiologic changes undergone by persons or animals who have become physically dependent on a drug or chemical due to prolonged use at elevated doses, but who are abruptly deprived of that substance. The abstinence syndrome varies with the drug to which dependence has developed. Generally the effects observed are in an opposite direction from those produced by the drug; e.g., the withdrawal syndrome from central nervous system depressants such as barbiturates and benzodiazepines consists of insomnia, restlessness, tremulousness, hallucinations, and, in the extreme, tonic-clonic convulsions which may prove fatal. The onset time and severity of the abstinence syndrome depend upon how rapidly the drug disappears from the body. (05 Mar 2000) |