| 영문 | steroid | 한글 | 스테로이드 |
|---|---|---|---|
| 설명 | Hydrogenated cyclopentanoperhydrophenanthrene ring system으로 구성된 분자. 생체내에서 중요한 스테로이드는 부신겉질에서 생성되는 스테로이드 호르몬이며 당대사에 관여하는 글루코코르티코이드(glucocorticoid), 염류대사(인체내 존재하는 염분성분(NaCl, KCl, NaOH 등)을 조절하는 대사)에 관여하는 광물코르티코이드(mineralocorticoid), 성호르몬(인체의 성발달에 관여)의 세 가지이다. 스테로이드 호르몬은 부신피질에서 콜레스테롤을 재료로 하여 복잡한 합성단계를 거쳐 합성된다. 글루코코르티코이드는 뇌하수체에서 분비되는 부신겉질자극 호르몬(ACTH)에 의해 생성과 분비가 이루어지나 광물코르티코이드는 레닌-안지오텐신계(신장에서 인체내 염분이 부족시 레닌이 분비되고, 이 자극은 부신으로 전해져 광물코르티코이드인 안지오텐신을 분비하게 됨)의 자극에 의해 분비된다. 글루코코르티코이드는 transcortin과 결합하여 운반되며 반감기는 한시간 정도이나 염류코르티코이드는 대부분이 단백질과 결합하지 않고 유리형으로 남아있어 반감기는 20분에 불과하다. 이들이 간에 도달하면 glucuronic acid에 결합하여 배설된다. |
||
| SSDD | steroid sulfatase deficiency disease |
|---|---|
| STS | sequence tagged site; serologic test for syphilis; sodium tetradecyl sulfate; sodium thiosulfate; st... |
| G6S | glucosamine-6-sulfatase |
| IDS | iduronate sulfatase; immune deficiency state; inhibitor of DNA synthesis; integrated delivery system... |
| MSD | material safety data; mean square deviation; mild sickle cell disease; most significant digit; multi... |
| STS | Steroid sulfatase |
|---|---|
| ARSA | Aryl sulfatase A |
| IDS | Iduronate sulfatase |
| MSD | Multiple Sulfatase Deficiency |
| AS | aryl sulfatase |
| steroid sulfatase deficiency | A form of ichthyosis, due to 3-beta-hydroxysteroidsulfate sulfatase deficiency, that appears at birth or in early infancy and affects males; characterised by scaling predominantly on the neck and trunk but not on the palms and soles; histologically, there is hyperkeratosis, a granular layer in the epidermis, and normal epidermal cell turnover. Synonym: steroid sulfatase deficiency. (05 Mar 2000) |
|---|
| bile salt sulfatase | <enzyme> Produces microorganism from the faecal flora of conventional rats Registry number: EC 3.1.6.- Synonym: bile acid sulfate sulfatase (26 Jun 1999) |
|---|---|
| galactose-6-sulfatase | <enzyme> An enzyme that eliminates sulfur from the galactose-6-sulfate residues of certain mucopolysaccharides, producing 3,6-anhydrogalactose residues; it is absent in Morquio's syndrome type A. Synonym: galactose-6-sulfurase. (05 Mar 2000) |
| glucuronate 2-sulfatase | <enzyme> does not act on iduronate-2-sulfate Registry number: EC 3.1.6.- Synonym: glucurono-2-sulfatase (26 Jun 1999) |
| cerebroside-sulfatase | <enzyme> An enzyme that catalyses the hydrolysis of cerebroside 3-sulfate (sulfatide) to yield a cerebroside and inorganic sulfate. A marked deficiency of arylsulfatase a, which is considered the heat-labile component of cerebroside sulfatase, has been demonstrated in all forms of metachromatic leukodystrophy (leukodystrophy, metachromatic). Chemical name: Cerebroside-3-sulfate 3-sulfohydrolase Registry number: EC 3.1.6.8 (12 Dec 1998) |
| chondro-2-sulfatase | <enzyme> Acts on d-glucuronate 2-sulfate units of chondroitin sulfate, heparin and heparan sulfate Registry number: EC 3.1.6.- (26 Jun 1999) |
| chondro-4-sulfatase | <enzyme> An arylsulfatase that catalyses the hydrolysis of the 4-sulfate groups of the disaccharide repeating units from chondroitin sulfate n-acetylgalactosamine 4-sulfate. The deficiency of chondro-4-sulfatase has been proposed as the defect in maroteaux-lamy syndrome (mucopolysaccharidosis vi). Chemical name: 4-Deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine-4-sulfate 4-sulfohydrolase Registry number: EC 3.1.6.9 (12 Dec 1998) |
| methylumbelliferone sulfatase | <enzyme> Used as test substrate for arylsulfatases Registry number: EC 3.1.6.- Synonym: 4-methylumbelliferone sulfate sulfatase (26 Jun 1999) |
| placental sulfatase deficiency | <enzyme> An enzyme defect in the placenta which results in failure of conversion of 16a-hydroxydehydroepiandrosterone to estriol; women with this condition rarely enter into spontaneous labour. (05 Mar 2000) |
| multiple sulfatase deficiency | An inherited disorder (autosomal recessive) in which there is a failure to hydrolyze sulfatides and sulfated mucopolysaccharides; this failure leads to their accumulation in neural and extraneural tissues causing demyelination, sulfatiduria, facial and skeletal dysmorphism, etc. (05 Mar 2000) |
| heparan N-sulfatase | <enzyme> An enzyme that participates in the stepwise degradation of heparan sulfate; heparan N-sulfatase hydrolyzes the sulfate moiety attached to the amino group of the glucosamine residue of heparan sulfate; a deficiency of this enzyme is associated with mucopolysaccharidose IIIA (Sanfilippo's syndrome A). (05 Mar 2000) |
| heparan sulfate sulfatase | <enzyme> Probable defect in sanfilippo a syndrome Registry number: EC 3.1.6.- Synonym: heparan sulphatase (26 Jun 1999) |
| N-acetylgalactosamine-6-sulfatase | <enzyme> Defective in mucopolysaccharidosis iva (morquio a) Registry number: EC 3.1.6.4 Synonym: n-acetylgalactosamine-6-sulfate sulfatase (26 Jun 1999) |
| N-acetylglucosamine-6-sulfatase | <enzyme> Deficient in sanfilippo syndrome type d Registry number: EC 3.1.6.14 Synonym: nagss, nagsase, glucosamine-6-sulfatase, n-acetylglucosamine-6-sulfate sulfatase (26 Jun 1999) |
| steryl-sulfatase | <enzyme> Arylsulfatases a and b hydrolyze nitrocatechol sulfate, but p-nitrophenyl sulfate is hydrolyzed only slightly by both enzymes; arylsulfatase c hydrolyzes both p-nitrophenyl sulfate and nitrocatechol sulfate, low substrate specificity located chiefly in microsomes; a and b are found in lysosomes; arylsulfatase a is cerebroside sulfatase and arylsulfatase b is chondro-4-sulfatase Registry number: EC 3.1.6.2 Synonym: arylsulfatase c, dehydroepiandrosterone sulfate sulfatase, steroid sulfatase, estrone sulfate sulfohydrolase, steroid sulphatase, cholesterol sulfatase, dhea sulfatase, 3 beta-hydroxysteroid sulfate sulfatase, estrone sulfate sulfatase, sterylsulfatase, steroid sulfohydrolase, cholesterol sulfate sulfatase, arylsulphatase c (26 Jun 1999) |
| N-sulfoglucosamine-3-sulfatase | <enzyme> Acts on n-acetylglucosamine-3-sulfate and n-sulfoglucosamine-3-sulfate Registry number: EC 3.1.6.15 Synonym: n-substituted glucosamine 3-o-sulphatase (26 Jun 1999) |
| steroid sulfatase |
steryl-sulfatase.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
|
|---|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|