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stem c. 1. any precursor cell.  2. a blood cell progenitor or mother cell representing a slightly later stage than the blast cell; it has the capacity for both replication and differentiation, and has pluripotentiality, giving rise to precursors of various different blood cell lines, such as the proerythrocyte and myeloblast, which cannot self-replicate and must differentiate into more mature daughter cells. Called also progenitor c., hematopoietic stem c., and colony-forming unit–spleen.
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