| SRC | sedimented red cells; sheep red cells |
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| src | Rous sarcoma oncogene |
| SH2 | SRC homology 2 |
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| SH | Src Homology |
| SH3 | Src Homology 3 |
| SH2 | Src homology domain 2 |
| SH3 | Src homology domain 3 |
| src homology domains | Regions of sequence similarity in the src family of cytoplasmic tyrosine kinases. The sh1 domain is a catalytic domain. Sh2 and sh3 domains are protein-binding domains. Sh2 usually binds phosphotyrosine-containing proteins and sh3 interacts with cytoskeletal proteins. (12 Dec 1998) |
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| beta-cell src-homology tyrosine kinase | <enzyme> A murine frk (fyn-related kinase) homolog; genbank l36132; do not confuse with brain-specific kinase bsk Registry number: EC 2.7.1.- Synonym: beta-cell sh tk, bsk protein, sh tk, bsk gene product, sh tk (26 Jun 1999) |
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| VH and VL genes/domains | VH and VL genes define in part the sequences of the variable heavy and light regions of immunoglobulin molecules. VH and VL domains are the regions of amino acid sequence so defined. J genes and, in the case of the heavy chain, a D gene (D=diversity) also define these regions. Gene rearrangement also plays a role in determining the sequences in which the genes are joined as the DNA of the immunoglobulin producing cell matures. (18 Nov 1997) |
| SH domains | <molecular biology> Src homology domains: domains of protein that, from their homology with src are involved in the interaction with phosphorylated tyrosine residues on other proteins (SH2 domains) or with proline rich sections of other proteins (SH3 domains). (18 Nov 1997) |
| domains | 1. Homologous units of approximately 110 to 120 amino acids each which comprise the light and heavy chains of the immunoglobulin molecule and which serve specific functions. The light chain has two domains's, one in the variable region and one in the constant region of the chain; the heavy chain has four to five domains's, depending upon the class of immunoglobulin, one in the variable region and the remaining ones in the constant region. 2. A region of a protein having some distinctive physical feature or role. Origin: Fr. Domaine, fr. L. Dominium, property, dominion (05 Mar 2000) |
| immunoglobulin domains | Structural units of immunoglobulin heavy or light chains that are composed of approximately 110 amino acids. Light chains of an immunoglobulin are composed of one constant domain and one variable domain. Heavy chains are composed of either three or four constant domains and one variable domain. (05 Mar 2000) |
| genes, src | Retrovirus-associated DNA sequences (src) originally isolated from the rous sarcoma virus (rsv). The proto-oncogene src (c-src) codes for a protein that is a member of the tyrosine kinase family and was the first proto-oncogene identified in the human genome. The human c-src gene is located at 20q12-13 on the long arm of chromosome 20. (12 Dec 1998) |
| proto-oncogene protein pp60(c-src) | <enzyme> Membrane-associated tyrosine-specific kinase encoded by the c-src genes. It has an important role in cellular growth control. Truncation of carboxy-terminal residues in pp60(c-src) leads to pp60(v-src) which has the ability to transform cells. This kinase pp60 c-src should not be confused with csk, also known as c-src kinase. Registry number: EC 2.7.1.- (12 Dec 1998) |
| homology | <embryology, genetics> Two anatomical structures or behavioural traits within different organisms which originated from a structure or trait of their common ancestral organism. The structures or traits in their current forms may not necessarily perform the same functions in each organism, nor perform the functions it did in the common ancestor. They may even have become completely unused and therefore vestigial. Compare: analogy. (09 Oct 1997) |
| homology of strands | homology of chains |
| sequence homology | <molecular biology> Strictly, refers to the situation where nucleic acid or protein sequences are similar because they have a common evolutionary origin. Often used loosely to indicate that sequences are very similar. Sequence similarity is observable, homology is an hypothesis based on observation. (18 Nov 1997) |
| sequence homology, amino acid | The degree of similarity between sequences of amino acids. This information is useful for the understanding of genetic relatedness of certain species. (12 Dec 1998) |
| sequence homology, nucleic acid | The sequential correspondence of nucleotide triplets in a nucleic acid molecule which permits nucleic acid hybridization. Sequence homology is important in the study of mechanisms of oncogenesis and also as an indication of the evolutionary relatedness of different organisms. The concept includes viral homology. (12 Dec 1998) |
| src | <molecular biology> The transforming (sarcoma inducing) gene of Rous sarcoma virus. The protein product is pp60vsrc, a cytoplasmic protein with tyrosine specific protein kinase activity, that associates with the cytoplasmic face of the plasma membrane. (12 Jan 1998) |
| src-family kinases | <enzyme> Family of non-receptor protein-tyrosine kinases homologous to src. They are closely related intracellular enzymes that participate in signal transduction pathways in a variety of haemopoietic cells and especially their surface receptors. Registry number: EC 2.7.1.- (12 Dec 1998) |
| src-related intestinal kinase | <enzyme> An intracellular epithelial cell tyrosine kinase; shares 80% homology with human tyrosine kinase brk; has 451 amino acid residues; amino acid sequence given in first source Registry number: EC 2.7.1.- Synonym: sik protein, sik gene product (26 Jun 1999) |
Synonyms : src Homology Region 2 Domain, Homology Domain, src, Homology Domains, src, SH Domain, SH1 Domains, SH2 Domains, SH3 Domains, src Homology Domain
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|