| squalene synthase | <enzyme> An enzyme that catalyses the formation of squalene from two molecules of farnesylpyrophosphate using NADPH and concomitant production of two molecules of pyrophosphate. (05 Mar 2000) |
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| squalene | <chemical> Chemical name: 2,6,10,14,18,22-Tetracosahexaene, 2,6,10,15,19,23-hexamethyl-, (all-E)- (12 Dec 1998) |
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| squalene cyclase | <enzyme> Nonoxidative conversion of squalene to tetrahymenol; does not go via 2,3-oxidosqualene Registry number: EC 4.- Synonym: squalene-tetrahydromanol cyclase (26 Jun 1999) |
| squalene epoxidase | <enzyme> An enzyme that catalyses the conversion of squalene to squalene 2,3-oxide in the endoplasmic reticulum; a required step in order for cyclization to occur, resulting in the synthesis of the first sterol, lanosterol, in steroidogenesis; uses NADPH. (05 Mar 2000) |
| squalene epoxidase-cyclase | <chemical> Consists of squalene epoxidase (EC 1.14.99.7) plus 2,3-oxidosqualene lanosterol-cyclase (EC 5.4.99.7) Chemical name: squalene-2,3-oxide lanosterol cyclase (26 Jun 1999) |
| squalene-hopene cyclase | <enzyme> From bacillus acidocaldarius; cyclises squalene into hopanoid triterpenes Registry number: EC 5.4.99.- Synonym: shc gene product (26 Jun 1999) |
| squalene synthetase | <enzyme> Catalyses the rearrangement and reduction of the cyclopropane compound, presqualene pyrophosphate to form squalene, with NADPH as the coenzyme. Registry number: EC 1.3.- (12 Dec 1998) |
| abequose synthase | <enzyme> Converts cdp-4-keto-3,6-dideoxy-d-glucose to cdp-3,6-dideoxy-d-galactose (cdp-abequose); requires NADPH, analogous to udp-glucose-4-epimerase Registry number: EC 5.1.3.- Synonym: rfbj gene product (26 Jun 1999) |
| acetoacetyl-acyl carrier protein synthase | <enzyme> E coli enzyme, that catalyses condensation of malonyl-acyl carrier protein plus acetyl-acyl carrier protein; not inhibited by cerulenin Registry number: EC 2.3.1.- Synonym: acetoacetyl-acp synthase (26 Jun 1999) |
| acetolactate synthase | <enzyme> A flavoprotein that catalyses the formation of acetolactate from 2 moles of pyruvate in the biosynthesis of valine and the formation of acetohydroxybutyrate from pyruvate and alpha-ketobutyrate in the biosynthesis of isoleucine. Chemical name: Acetolactate pyruvate-lyase (carboxylating) Registry number: EC 4.1.3.18 (12 Dec 1998) |
| acridone synthase | <enzyme> Catalyses the condensation of n-methylanthraniloyl-CoA and 3 malonyl-CoA to produce 1,3-dihydroxy-n-methylacridone Registry number: EC 2.3.1.- (26 Jun 1999) |
| acyl-malonyl-ACP synthase | <enzyme> An enzyme condensing malonyl-ACP and acyl-cys-protein to 3-oxoacyl-ACP + cys-protein + CO2, and similar reactions, as steps in fatty acid synthesis; cys-protein is also a part of the fatty acid synthase complex. Synonym: acyl-malonyl-ACP synthase, beta-ketoacyl-ACP synthase. (05 Mar 2000) |
| adenylosuccinate synthase | <enzyme> A carbon-nitrogen ligase. During purine ribonucleotide biosynthesis, this enzyme catalyses the synthesis of adenylosuccinate from GTP, imp, and aspartate with the formation of orthophosphate and GDP. Chemical name: IMP:L-aspartate ligase (GDP-forming) Registry number: EC 6.3.4.4 (12 Dec 1998) |
| adenylylosuccinate synthase | <enzyme> A carbon-nitrogen ligase. During purine ribonucleotide biosynthesis, this enzyme catalyses the synthesis of adenylosuccinate from GTP, imp, and aspartate with the formation of orthophosphate and GDP. Chemical name: IMP:L-aspartate ligase (GDP-forming) Registry number: EC 6.3.4.4 (12 Dec 1998) |
| agropine synthase | <enzyme> Final enzyme in the three enzyme pathway for agropine synthesis; cyclises deoxymannityl-glutamine to the lactone, agropine Registry number: EC 4.2.1.- Synonym: ags gene product (26 Jun 1999) |
| alkylglycerone-phosphate synthase | <enzyme> Replaces the acyl moiety of acyldhap with a long chain fatty alcohol; intact alcohol including the oxygen atom is incorporated into alkyl-dhap Registry number: EC 2.5.1.26 Synonym: adhps, alkyl-dihydroxyacetone phosphate synthase, alkyl-dhap synthase, alkyldihydroxyacetone phosphate synthetase, acylglycerone-3-phosphate-long chain-alcohol o-3-phospho-2-oxopropanyl transferase, alkyldihydroxyacetonephosphate synthase (26 Jun 1999) |