| splitting | In chemistry, the cleavage of a covalent bond, fragmenting the molecule involved. (05 Mar 2000) |
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| splitting enzymes | Enzyme's that, like aldolases, catalyze the conversion of a molecule into two smaller molecules without the addition or subtraction of any atoms. (05 Mar 2000) |
| splitting of heart sounds | The production of major components of the first and second heart sounds (rarely the third and fourth) due to contribution by the left-sided and right-sided valves; thus, the first heart sound would have a mitral and a tricuspid component and the second heart sound has an aortic and pulmonic component. The latter are best appreciated during respiration, with inspiration delaying the pulmonic component and producing an earlier aortic component. (05 Mar 2000) |
| kinase-splitting membranal proteinase | <enzyme> Brush-border membrane proteinase; specifically clips the native form of the catalytic subunit of camp-dependent protein kinase Registry number: EC 3.4.99.- Synonym: ksm proteinase (26 Jun 1999) |
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