| sphingol | <biochemistry> Long chain amino alcohol that bears an approximate similarity to glycerol with a hydrophobic chain attached to the 3 carbon. Forms the class of sphingolipids when it carries an acyl group joined by an amide link to the nitrogen. Forms sphingomyelin when phosphoryl choline is attached to the 1 hydroxyl group. Gives rise to the cerebroside and ganglioside classes of glycolipids when oligosaccharides are attached to the 1 hydroxyl group. Not found in the free form. (18 Nov 1997) |
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| sphingolipid | <biochemistry> Structural lipid of which the parent structure is sphingosine rather than glycerol. Synthesised in the Golgi complex. (18 Nov 1997) |
| sphingolipid ceramide N-deacylase | <enzyme> Hydrolyzes the n-acyl linkage between fatty acids and sphingosine bases in ceramides in various sphingolipids, as well as sphingomyelin to produce their lyso forms; mw 52 kD Registry number: EC 3.5.1.- Synonym: scdase (26 Jun 1999) |
| sphingolipidoses | Lysosomal storage diseases characterised by failure to degrade sphingolipids and resulting in their abnormal storage. (12 Dec 1998) |
| sphingolipidosis | Collective designation for a variety of diseases characterised by abnormal sphingolipid metabolism, e.g., gangliosidosis, Gaucher's disease, Niemann-Pick disease. Synonym: sphingolipodystrophy. (05 Mar 2000) |
| sphingolipodystrophy | Collective designation for a variety of diseases characterised by abnormal sphingolipid metabolism, e.g., gangliosidosis, Gaucher's disease, Niemann-Pick disease. Synonym: sphingolipodystrophy. (05 Mar 2000) |