| specific | 1. Pertaining to a species. 2. Produces by a single kind of microorganism. 3. A remedy specially indicated for any particular disease. 4. <immunology> Pertaining to the special affinity of antigen for the corresponding antibody. Origin: L. Specificus (18 Nov 1997) |
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| specific absorbance | Absorbance per unit of concentration. See: specific absorption coefficient. (05 Mar 2000) |
| specific absorption coefficient | Absorbance (of light) per unit path length (usually the centimeter) and per unit of mass concentration. Compare: molar absorption coefficient. Synonym: absorbancy index, absorptivity, extinction coefficient, specific extinction. (05 Mar 2000) |
| specific action | The action of a drug or a method of treatment which has a direct and especially curative effect upon a disease, e.g., the action of vitamin B12 in pernicious anaemia. (05 Mar 2000) |
| specific active immunity | See: acquired immunity. (05 Mar 2000) |
| specific activity | 1. <chemistry> The number of activity units (whatever is appropriate) per unit of mass, volume or molarity. 2. <radiobiology> Total activity of a given nuclide per gram of a compound, element or radioactive nuclide. Perhaps most often usage, in the context of radiochemicals, the number of microcuries per micromole. (16 Dec 1997) |
| specific anergy | A reduction of the normal or usual immunologic response resulting from a reaction to a specific allergen. Synonym: specific anergy. (05 Mar 2000) |
| specific antigens | Antigen's that characterise a single genus of microorganisms. (05 Mar 2000) |
| specific antiserum | See: antiserum. (05 Mar 2000) |
| specific capsular substance | A soluble type-specific polysaccharide produced during active growth of virulent pneumococci composing a large part of the capsule. Synonym: pneumococcal polysaccharide, soluble specific substance, specific soluble polysaccharide, specific soluble sugar. (05 Mar 2000) |
| specific cause | A cause the action of which definitely produces the condition in question. (05 Mar 2000) |
| specific cholinesterase | <enzyme, neurology, physiology> An enzyme that breaks down unused acetylcholine in the synaptic cleft (the space between neurons), this enzyme is necessary to restore the synaptic cleft so it is ready to transmit the next nerve impulse. (06 May 1997) |
| specific compliance | The compliance of a structure divided by its initial volume, more specifically for the lungs, the compliance divided by the functional residual capacity. (05 Mar 2000) |
| specific disease | A disease produced by the action of a special pathogenic microorganism. (05 Mar 2000) |
| specific dynamic action | The increase of heat production caused by the ingestion of food, especially of protein. (05 Mar 2000) |
| site-specific DNA-methyltransferase (adenine-specific) | <enzyme> An enzyme responsible for producing a species-characteristic methylation pattern on adenine residues in a specific short base sequence in the host cell DNA. The enzyme catalyses the methylation of DNA adenine in the presence of s-adenosyl-l-methionine to form DNA containing 6-methylaminopurine and s-adenosyl-l-homocysteine. Registry number: EC 2.1.1.72 (12 Dec 1998) |
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| site-specific DNA methyltransferase (cytosine-specific) | <enzyme> An enzyme responsible for producing a species-characteristic methylation pattern on cytosine residues in a specific short base sequence in the host cell's DNA. The enzyme catalyses the methylation of DNA cytosine in the presence of s-adenosyl-l-methionine to form s-adenosyl-l-homocysteine and DNA containing 5-methylcytosine. Registry number: EC 2.1.1.73 (12 Dec 1998) |
| age-specific rate | A rate for a specified age group, in which the numerator and denominator refer to the same age group. (05 Mar 2000) |
| Bensley's specific granules | Granule's in the cells of the islands of Langerhans in the pancreas. (05 Mar 2000) |
| brain-specific kinase | <enzyme> Expressed specifically in brain; member of the eph/elk receptor-like kinase family; mw 105 kD; may represent murine homolog of chicken cek7 receptor-like kinase; amino acid sequence given in first source Registry number: EC 2.7.1.- Synonym: bsk tyrosine kinase (26 Jun 1999) |
| galactosyl-1-3-N-acetylgalactosaminyl-specific 2,6-sialyltransferase | <enzyme> Genbank x77775 Registry number: EC 2.4.99.- Synonym: galbeta1,3galnac 2,6-sialyltransferase, st6galnac II (26 Jun 1999) |
| glycoprotein hormone-specific N-acetylgalactosamine transferase | <enzyme> Transfers galnac to the terminal glcnac moieties of glcnac2man3glcnac2asn Registry number: EC 2.4.1.- Synonym: ghs-acgalnh2 transferase, glycoprotein hormone galnac transferase, glycoprotein hormone - n-acetylgalactosaminyltransferase (26 Jun 1999) |
| retina-specific amine oxidase | <enzyme> Genbank d88213 Registry number: EC 1.4.- Synonym: rao enzyme, human (26 Jun 1999) |
| Gomori's non-specific acid phosphatase stain | <technique> A method in which formalin-fixed frozen sections are incubated in a substrate containing sodium beta-glycerophosphate and lead nitrate at pH 5.0; the insoluble lead phosphate produced is treated with ammonium sulfide to give a black lead sulfide. (05 Mar 2000) |
| Gomori's non-specific alkaline phosphatase stain | <technique> A calcium-cobalt sulfide method using frozen sections or cold acetone-or formalin-fixed paraffin sections, plus sodium beta-glycerophosphate as a substrate at pH 9.0 to 9.5 with Mg++ as activator; calcium ions precipitate the liberated phosphate, cobalt salt replaces the calcium phosphate, and ammonium sulfide converts the product to a black cobalt sulfide. (05 Mar 2000) |
| group-specific protease | <enzyme> A serine protease, obtained from rat small intestine, which preferentially inactivates the apo forms of certain pyridoxal phosphate requiring enzymes Registry number: EC 3.4.21.- (26 Jun 1999) |
| RNA, transfer, amino acid-specific | A group of transfer rnas which are specific for carrying each one of the 20 amino acids to the ribosome in preparation for protein synthesis. (12 Dec 1998) |
| poly A specific exoribonuclease | <enzyme> Acts on 2' or 3'-linked oligoriboadenylates to liberate 5'-AMP Registry number: EC 3.1.13.- Synonym: 2',3'-exoribonuclease, 3'-exoribonuclease (26 Jun 1999) |
| poly(A)-specific ribonuclease | <enzyme> From vigna unguiculata seedlings; bifunctional enzyme responsible for both poly(a)-polymerizing and poly(a)-hydrolyzing activities; removes the poly(a) tail as the first step in degrading mRNA Registry number: EC 3.1.13.4 Synonym: poly(a) nuclease, mRNA poly(a) nuclease, poly(a) ribonuclease (pan), pan2 protein (26 Jun 1999) |
| myelencephalon-specific serine protease | <enzyme> Specifically expressed in the nervous system; plays a role in normal homeostasis and response of spinal cord to injury. Registry number: EC 3.4.21.- Synonym: myelencephalon-specific protease, msp enzyme (26 Jun 1999) |