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genetic engineering <molecular biology, technique> General term covering the use of various experimental techniques to produce molecules of DNA containing new genes or novel combinations of genes, usually for insertion into a host cell for cloning.
(07 May 1998)
genetic engineering technologies See: recombinant DNAtechnologies.
(09 Oct 1997)
somatic cell Usually any cell of a multicellular organism that will not contribute to the production of gametes, i.e. most cells of which an organism is made: not a germ cell. Notice, however, the alternative use in somatic mesoderm.
(18 Nov 1997)
somatic cell gene therapy The repair or replacement of a defective gene within somatic tissue.
(09 Oct 1997)
somatic cell genetics Method for identifying the chromosomal location of a particular gene without sexual crossing. Unstable heterokaryons are made between the cell of interest and another cell with identifiably different characteristics (or without the gene in question) and a series of clones isolated. By correlating retention of gene expression with the remaining chromosomes, it is possible to deduce which chromosome must carry the gene. Human mouse heterokaryons have been extensively used in this sort of work.
(18 Nov 1997)
somatic cell hybridization Production of a heterokaryon.
(05 Mar 2000)
biological engineering <agriculture> A type of artificial selection, the creation of plant or animal breeds that are agriculturally or industrially useful.
Compare: natural selection.
(21 Mar 1998)
biomedical engineering <orthopaedics> The use of engineering technology, instrumentation and methods to solve medical problems, such as improving our understanding of physiology and the manufacture of artificial limbs and organs.
(21 Mar 1998)
biotechnical engineering Civil engineering methods incorporating organic materials to produce functional structures that are also aesthetically pleasing, provide wildlife habitat, and provide sites for revegetation.
(09 Oct 1997)
maintenance and engineering, hospital Hospital department whose primary function is the upkeep and supervision of the buildings and grounds and the maintenance of hospital physical plant and equipment which requires engineering expertise.
(12 Dec 1998)
cellular engineering <technique> The use of techniques for constructing replacement or additional or experimental parts of cells and tissues for both fundamental investigation and as prosthetic devices. Often involves the interfacing of cells and nonliving structures.
(26 Mar 1998)
sanitary engineering A branch of engineering concerned with the design, construction, and maintenance of environmental facilities conducive to public health, such as water supply and waste disposal.
(12 Dec 1998)
protein engineering Normally means the use of recombinant DNA technology to produce proteins with desired modifications in the primary sequence.
See: site specific mutagenesis.
(18 Nov 1997)
human engineering The science of designing, building or equipping mechanical devices or artificial environments to the anthropometric, physiological, or psychological requirements of the people who will use them.
(12 Dec 1998)
dental engineering <dentistry> Application of engineering principles to dentistry.
(05 Mar 2000)
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