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fluorescein <chemical> Fluorophore commonly used in microscopy.
Fluorescein di acetate can be used as a vital stain or can be conjugated to proteins (particularly antibodies) using isothiocyanate.
Excitation is at 365nm and the emitted light is green yellow (450-490nm). The emission spectrum is pH sensitive and fluorescein can therefore be used to measure pH in intracellular compartments.
(18 Nov 1997)
fluorescein-5-isothiocyanate <chemical> 3',6'-dihydroxy-5-isothiocyanatospiro(isobenzofuran-1(3h),9'-(9h)xanthen)-3-one. Fluorescent probe capable of being conjugated to tissue and proteins. It is used as a label in fluorescent antibody staining procedures as well as protein- and amino acid-binding techniques.
Pharmacological action: fluorescent dyes.
Chemical name: Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 3',6'-dihydroxy-5-isothiocyanato-
(12 Dec 1998)
fluorescein angiography <procedure> The process of taking X-rays of blood vessels that have been injected with a special dye. The dye allows to person viewing the X-ray to see the blood vessels.
(13 Nov 1997)
fluorescein-conjugated antibody Refers to an antibody that has joined with a fluorescein molecule.
(09 Oct 1997)
fluorescein eye examination A special test that allows the examiner to detect cornea abrasions or corneal foreign bodies. An orange dye (fluorescein) is placed into the eye and the eye is illuminated with a cobalt blue light (black light). This serves to highlight any irregularities in the corneal surface.
(27 Sep 1997)
fluorescein instillation test A test for patency of the lacrimal system; fluorescein instilled in the conjunctival sac can be recovered from the inferior nasal meatus.
Synonym: Jones' test.
(05 Mar 2000)
fluorescein isothiocyanate <chemical> A fluorescent chemical derived from fluorescein which is used to label proteins.
(25 Jun 1999)
fluorescein sodium A dye used for diagnosis of certain ocular diseases, differentiation or delineation of organ parts in surgery, and determination of circulation time.
Synonym: resorcinolphthalein sodium, uranin.
(05 Mar 2000)
fluorescein string test A string test used to determine location of a bleeding intestinal lesion in which fluorescein is given intravenously to determine gastrointestinal haemorrhage; if the string fluoresces after removal, it has been contaminated by blood that has appeared since injection of the fluorescein; used to determine location of bleeding lesion.
(05 Mar 2000)
3-O-methyl-fluorescein phosphatase <enzyme> Used for assay of na-k-atpase in intact tissues
Registry number: EC 3.6.1.-
Synonym: 3-o-methylfluorescein phosphatase
(26 Jun 1999)
acid soluble spore protein <molecular biology> A DNA binding protein in the spores of some bacteria, thought to stabilise the DNA in an A configuration, so protecting it from cleavage by enzymes or UV light.
(18 Nov 1997)
alcohol-soluble eosin See: ethyl eosin.
Synonym: alcohol-soluble eosin.
(05 Mar 2000)
water-soluble chlorophyll derivatives The copper complex of sodium and/or potassium salts of saponified chlorophyll, used topically for deodorization of chronic lesions and to promote wound repair.
(05 Mar 2000)
soluble 1. Susceptible of being dissolved in a fluid; capable of solution; as, some substances are soluble in alcohol which are not soluble in water. "Sugar is . . . Soluble in water and fusible in fire." (Arbuthnot)
2. Susceptible of being solved; as, a soluble algebraic problem; susceptible of being disentangled, unraveled, or explained; as, the mystery is perhaps soluble. "More soluble is this knot."
3. Relaxed; open or readily opened. "The bowels must be kept soluble." Soluble glass.
<chemistry> See Glass.
Origin: L. Solubilis, fr. Solvere, solutum, to loosen, to dissolve: cf. F. Soluble. See Solve, and cf. Solvable.
Source: Websters Dictionary
(01 Mar 1998)
soluble antigen Viral antigen that remains in solution after the particles of virus have been removed by means of centrifugation; in the case of the influenza viruses, it is the internal helical structure, free of the external envelope.
Synonym: S antigen.
(05 Mar 2000)
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