| slow reacting substance of anaphylaxis | <immunology> Potent bronchoconstrictor and inflammatory agent released by mast cells, an important mediator of allergic bronchial asthma. A mixture of three leukotrienes (LTC4 mainly, LTD4 and LTE4) (18 Nov 1997) |
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| slow-reacting substance | Slow-reacting substance of anaphylaxis (SRS-A), a leukotriene of low molecular weight which is released in anaphylactic shock and produces slower and more prolonged contraction of muscle than does histamine; it is active in the presence of antihistamines (but not epinephrine) and seems not to occur preformed in mast cells, but as a result of an antigen-antibody reaction on the granules. Compare: peptidyl leukotrienes. Synonym: slow-reacting factor of anaphylaxis. (05 Mar 2000) |
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| slow-reacting factor of anaphylaxis | Slow-reacting substance of anaphylaxis (SRS-A), a leukotriene of low molecular weight which is released in anaphylactic shock and produces slower and more prolonged contraction of muscle than does histamine; it is active in the presence of antihistamines (but not epinephrine) and seems not to occur preformed in mast cells, but as a result of an antigen-antibody reaction on the granules. Compare: peptidyl leukotrienes. Synonym: slow-reacting factor of anaphylaxis. (05 Mar 2000) |
| minimal reacting dose | The minimal dose of a toxic substance causing a reaction, as manifested in the skin of a series of susceptible test animals; the assay is based on the development of a characteristic, minimal but definite, "standard," focal inflammation (congestion and oedema, induration, degenerative changes, and desquamation of epidermal cells). (05 Mar 2000) |
| cross-reacting agglutinin | An immune agglutinin specific for a group antigen. Synonym: cross-reacting agglutinin. (05 Mar 2000) |
| cross-reacting antibody | <immunology> Antibody specific for group antigens, i.e., those with identical functional groups, antibody for antigens that have functional groups of closely similar, but not identical, chemical structure. (05 Mar 2000) |
| cross-reacting material | <haematology> A substance sufficiently different from a reference substance (R) to have a perceptibly different function from R but sufficiently similar to R that it reacts with anti-R antibodies; e.g., mutant factor VIII may be defective or even inert in coagulation and yet be immunologically identified as factor VIII. (05 Mar 2000) |
| direct reacting bilirubin | The fraction of serum bilirubin which has been conjugated with glucuronic acid in the liver cell to form bilirubin diglucuronide; so called because it reacts directly with the Ehrlich diazo reagent; increased levels are found in hepatobiliary diseases, especially of the obstructive variety. Synonym: conjugated bilirubin. (05 Mar 2000) |
| indirect reacting bilirubin | The fraction of serum bilirubin which has not been conjugated with glucuronic acid in the liver cell; so called because it reacts with the Ehrlich diazo reagent only when alcohol is added; increased levels are found in hepatic disease and haemolytic conditions. Synonym: unconjugated bilirubin. (05 Mar 2000) |
| arrhythmias, slow | Abnormally slow heart rhythms, medically termed bradycardia. (12 Dec 1998) |
| slow | To go slower; often with up; as, the train slowed up before crossing the bridge. 1. Moving a short space in a relatively long time; not swift; not quick in motion; not rapid; moderate; deliberate; as, a slow stream; a slow motion. 2. Not happening in a short time; gradual; late. "These changes in the heavens, though slow, produced Like change on sea and land, sidereal blast." (Milton) 3. Not ready; not prompt or quick; dilatory; sluggish; as, slow of speech, and slow of tongue. "Fixed on defense, the Trojans are not slow To guard their shore from an expected foe." (Dryden) 4. Not hasty; not precipitate; acting with deliberation; tardy; inactive. "He that is slow to wrath is of great understanding." (Prov. Xiv. 29) 5. Behind in time; indicating a time earlier than the true time; as, the clock or watch is slow. 6. Not advancing or improving rapidly; as, the slow growth of arts and sciences. 7. Heavy in wit; not alert, prompt, or spirited; wearisome; dull. Slow is often used in the formation of compounds for the most part self-explaining; as, slow-gaited, slow-paced, slow-sighted, slow-winged, and the like. Slow coach, a slow person. See def.7, above. <zoology> Slow lemur, or Slow loris, an East Indian nocturnal lemurine animal (Nycticebus tardigradus) about the size of a small cat; so called from its slow and deliberate movements. It has very large round eyes and is without a tail. Called also bashful Billy. Slow match. See Match. Synonym: Dilatory, late, lingering, tardy, sluggish, dull, inactive. Slow, Tardy, Dilatory. Slow is the wider term, denoting either a want of rapid motion or inertness of intellect. Dilatory signifies a proneness to defer, a habit of delaying the performance of what we know must be done. Tardy denotes the habit of being behind hand; as, tardy in making up one's acounts. Origin: OE. Slow, slaw, AS. Slaw; akin to OS. Slu blunt, dull, D. Sleeuw, slee, sour, OHG. Slo blunt, dull, Icel. Slr, slr, Dan. Slov, Sw. Slo. Cf. Sloe, and Sloth. Source: Websters Dictionary (01 Mar 1998) |
| slow channel-blocking agent | calcium channel-blocking agent |
| slow combustion | See: decay. Spontaneous combustion, the ignition of a mass of material by heat developed within it by the oxidation of the substances composing it without external ignition. (05 Mar 2000) |
| slow fever | A continued fever of long duration. (05 Mar 2000) |
| slow muscle | <physiology> Striated muscle used for long term activity (e.g. Postural support). Depend therefore on oxidative metabolism and have many mitochondria and abundant myoglobin. (18 Nov 1997) |
| slow pyrolysis | Thermal conversion of biomass to fuel by slow heating to less than 450>C in the absence of oxygen. (05 Dec 1998) |