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sex-linked <genetics> A genetic disorder where the genetic defect is linked to one of the chromosomes that determines sex (x or y). This is usually due to a gene on the unpaired portion of the X chromosome. Recessive X linked alleles are fully expressed in the heterogametic sex because they can have only one copy of the gene. Thus X linked mutant disorders are more common in human males than in females.
An example is haemophilia, which is autosomal recessive and linked to the X chromosome, so only males (XY) actually manifest the disease.
(06 Oct 1997)
sex-linked character An inherited character determined by a gene on a gonosome.
See: gene.
(05 Mar 2000)
sex-linked inheritance The pattern of inheritance that may result from a mutant gene located on either the X or Y chromosome.
(05 Mar 2000)
sex-linked locus Any locus that in normal karyotypes is borne on a heterosome; commonly but incorrectly applied to an X-linked locus.
(05 Mar 2000)
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