| congenital severe combined immunodeficiency | Disease, one form of which is caused by the lack of a transcription factor required for expression of HLA class II genes. (18 Nov 1997) |
|---|---|
| severe combined immunodeficiency | Group of rare congenital disorders characterised by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels. It is inherited as an x-linked or autosomal recessive defect. About half of the patients with autosomal recessive scid are deficient in the enzyme adenosine deaminase. (12 Dec 1998) |
| severe combined immunodeficient mice | Mice that lack both T and B lymphocytes and are used for transplantation and study of human lymphoid tissues resulting in a SCID-human mouse chimera. See: severe combined immunodeficiency. (05 Mar 2000) |
| combined immunodeficiency | <immunology> Congenital immunodeficiency with thymic agenesis, lymphocyte depletion and hypogammaglobulinaemia: both cellular and humoral immune systems are affected and life expectancy is low unless marrow transplantation is successful. (18 Nov 1997) |
| combined immunodeficiency syndrome | <syndrome> A serious primary immunodeficiency affecting both T and B-cells. (05 Mar 2000) |
| severe postanoxic encephalopathy | Coma that develops a few days to 3 weeks after an acute hypoxic insult; the latter was usually severe enough to cause an initial bout of coma, which cleared, and was followed by a transient interval of apparent normality. Synonym: severe postanoxic encephalopathy. (05 Mar 2000) |
| combined system disease | A subacute or chronic disorder of the spinal cord, such as that occurring in certain patients with vitamin B12 deficiency, characterised by a slight to moderate degree of gliosis in association with spongiform degeneration of the posterior and lateral columns. Synonym: combined sclerosis, combined system disease, funicular myelitis, Putnam-Dana syndrome, vitamin B12 neuropathy. (05 Mar 2000) |
| acquired immunodeficiency disease | Acquired immunodeficiency disease: Disease caused by infection with the human immunodeficiency virus (HIV). (12 Dec 1998) |
| anaesthetics, combined | The use of two or more chemicals simultaneously or sequentially to induce anaesthesia. The drugs need not be in the same dosage form. (12 Dec 1998) |
| antibiotics, combined | Combination of antibiotics used against difficult-to-treat infections. Antibiotic combinations have been used mainly to broaden the antibacterial spectrum and prevent development of resistance. In some instances these combinations have shown lower toxicity, but drug antagonism may be one of the problems encountered by their use. They may be given simultaneously or sequentially. The drugs need not be in the same dosage form. (12 Dec 1998) |
| antineoplastic agent, combined | The use of two or more chemicals simultaneously or sequentially in the drug therapy of neoplasms. The drugs need not be in the same dosage form. (12 Dec 1998) |
| vaccines, combined | Two or more vaccines in a single dosage form. (12 Dec 1998) |
| combined cycle | Two or more generation processes in series or in parallel, configured to optimise the energy output of the system. (05 Dec 1998) |
| combined-cycle power plant | The combination of a gas turbine and a steam turbine in an electric generation plant. The waste heat from the gas turbine provides the heat energy for the steam turbine. (05 Dec 1998) |
| combined fat-and carbohydrate-induced hyperlipaemia | Hyperlipoproteinaemia characterised by increased plasma levels of chylomicrons, VLDL, pre-beta-lipoproteins, and triglycerides, and slight rise of cholesterol on a normal diet, with beta-lipoproteins normal; may be accompanied by bouts of abdominal pain, hepatosplenomegaly, susceptibility to atherosclerosis, and abnormal glucose tolerance; probably autosomal recessive inheritance. Synonym: combined fat-and carbohydrate-induced hyperlipaemia, familial hyperchylomicronaemia with hyperprebetalipoproteinaemia, mixed hyperlipaemia. (05 Mar 2000) |