| selectin | <protein> Group of cell adhesion molecules that bid to carbohydrates via a lectin like domain. The name is derived from select and lectin. They are integral membrane glycoproteins with an N terminal, C type lectin domain, followed by an EGF like domain, a variable number of repeats of the short consensus sequence of complement regulatory proteins and a single transmembrane domain. Three selectins have been identified and are distinguished by capital letters based on the source of the original identification i.e. E selectin, L selectin and P selectin. (18 Nov 1997) |
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| selectins | Family of cell adhesion molecules consisting of a lectin-like domain, an epidermal growth factor-like domain, and a variable number of domains that encode proteins homologous to complement-binding proteins. Selectins mediate the binding of leukocytes to the vascular endothelium. (12 Dec 1998) |
| p-selectin | <cell biology> Cell adhesion molecule and CD antigen that mediates the adhesion of neutrophils and monocytes to activated platelets and endothelial cells. (12 Dec 1998) |
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| e-selectin | Cell adhesion molecule and CD antigen that mediates neutrophil, monocyte, and memory T-cell adhesion to cytokine-activated endothelial cells. E-selectin recognises sialylated carbohydrate groups related to the lewis x or lewis a family. (12 Dec 1998) |
| l-selectin | Cell adhesion molecule and CD antigen that serves as a homing receptor for lymphocytes to lymph node high endothelial venules. (12 Dec 1998) |