| chromosome segregation | <cell biology> The orderly separation of one copy of each chromosome into each daughter cell at mitosis. (18 Nov 1997) |
|---|---|
| mitotic segregation | <genetics> Mitotic recombination. (18 Nov 1997) |
| segregation | 1. The act of segregating, or the state of being segregated; separation from others; a parting. 2. <geology> Separation from a mass, and gathering about centers or into cavities at hand through cohesive attraction or the crystallizing process. Origin: L. Segregatio: cf. F. Segregation. Source: Websters Dictionary (01 Mar 1998) |
| segregation analysis | In genetics, the enumeration of progeny according to distinct and mutually exclusive phenotypes; used as a test of a putative pattern of inheritance, e.g., mendelian, dominant autosomal, epistatic, age-dependent. (05 Mar 2000) |
| segregation of chromosomes | <cell biology, genetics> The separation of pairs of homologous chromosomes that occurs at meiosis so that only one chromosome from each pair is present in any single gamete. (18 Nov 1997) |
| segregation ratio | In genetics, the proportion of progeny of a particular genotype or phenotype from actual matings of specified genotypes. The test of a Mendelian hypothesis is the comparison of the segregation rate with the Mendelian rate. (05 Mar 2000) |
| law of segregation | Factors that affect development retain their individuality from generation to generation, do not become contaminated when mixed in a hybrid, and become sorted out from one another when the next generation of gametes is formed. Synonym: Mendel's first law. (05 Mar 2000) |
| adaptor hypothesis | A hypothesis, proposed by F.H.C. Crick, that an adaptor molecule must be present between the information-containing DNA and the protein being synthesised. (05 Mar 2000) |
| altered self hypothesis | The hypothesis that the T-cell receptor in MHC mediated phenomena recognises a syngeneic MHC Class I or Class II molecule after modification by a virus or certain chemicals. See: MHC restriction. (18 Nov 1997) |
| alternative hypothesis | In Neyman-Pearson testing of a hypothesis, the hypothesis or family of hypotheses about the numerical value of a parameter if and only if the null hypothesis is rejected as untenable. (05 Mar 2000) |
| autocrine hypothesis | That tumour cells containing viral oncogenes may have encoded a growth factor, normally produced by other cell types, and thereby produce the factor autonomously, leading to uncontrolled proliferation. (05 Mar 2000) |
| Avogadro's hypothesis | <physics> The hypothesis that equal volumes of two different gases at the same temperature and pressure contain the same number of molecules. (02 Jan 1998) |
| Bayesian hypothesis | An array of surmised values of a parameter to be severally explored in the light of a current set of data, with logical symmetry being preserved among all. The merits of each hypothesis entertained are based on quantity, the prior probability. The probability of the data conditional on the hypothesis is computed as the conditional probability for each; the product of the two for each hypothesis is the joint probability, and the ratio of each joint probability to the sum of all the joint probabilities is the posterior probability for that hypothesis. Unlike the Neyman-Pearson test of hypotheses, the answer is a statement about the hypothesis, not about the sample conditional on the hypothesis. No hypothesis is preferred or prevails by default. The procedure may be applied recursively any number of times, as the data becomes available. (05 Mar 2000) |
| Makeham's hypothesis | A development of Gompertz' hypothesis as to the force of mortality following some mathematical law. Makeham assumed that death was the consequence of two generally coexisting causes: 1) chance; 2) a deterioration or increased inability to withstand destruction. The first of these is constant, the second is an increasing geometrical progression. (05 Mar 2000) |
| gate-control hypothesis | A theory to explain the mechanism of pain; small fibre afferent stimuli, particularly pain, entering the substantia gelatinosa can be modulated by large fibre afferent stimuli and descending spinal pathways so that their transmission to ascending spinal pathways is blocked (gated). Synonym: gate-control hypothesis. (05 Mar 2000) |