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sedimentation coefficient the velocity at which a particle sediments in a centrifuge divided by the applied centrifugal field, the result having units of time (velocity divided by acceleration), usually expressed in Svedberg units (S), which equal 10 -13 second. Sedimentation coefficients are used to characterize the size of macromolecules, eg, 5.8S rRNA, 22S rRNA; they increase with increasing mass and density and are higher for globular than for fibrous particles. Called also sedimentation constant.
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