| retroperitoneal liposarcoma | <radiology> Most common primary retroperitoneal tumour, rarely arises from lipoma, 95% of all fatty retroperitoneal tumours, 40-60 years; M>F, most radiosensitive sarcoma (32% 5-year survival) findings, CT, contrast enhancement, mixed density (fat and soft tissue elements), pseudocystic pattern: water density secondary to volume averaging, angio: hypovascular; no vessel dilation, capillary staining, laking sites for liposarcoma: lower extremity 45%, abdominal cavity and retroperitoneum 14%, trunk 14%, upper extremity 8%, head and neck 7% (12 Dec 1998) |
|---|---|
| liposarcoma | A malignant tumour derived from primitive or embryonal lipoblastic cells. It may be composed of well-differentiated fat cells or may be dedifferentiated: myxoid (liposarcoma, myxoid), round-celled, or pleomorphic, usually in association with a rich network of capillaries. Recurrences are common and dedifferentiated liposarcomas metastasize to the lungs or serosal surfaces. (12 Dec 1998) |
| liposarcoma, myxoid | A liposarcoma containing myxomatous tissue. (12 Dec 1998) |
| radial sclerosing lesion | A variant of sclerosing adenosis of the breast with central scar formation and radiating hyperplastic ducts. Synonym: radial scar. (05 Mar 2000) |
| cholangitis, sclerosing | Chronic, nonbacterial inflammatory narrowing of the bile ducts. About 50% of the cases are associated with ulcerative colitis. Treatment is to relieve the obstruction by balloon dilatation or surgery. (12 Dec 1998) |
| chronic diffuse sclerosing osteomyelitis | A proliferative reaction of bone to a low-grade infection of the jaws; most often seen in middle-aged or older black women as extensive, often bilateral radio-opacities of the mandible and maxilla. (05 Mar 2000) |
| chronic focal sclerosing osteomyelitis | A reaction of bone to a mild bacterial infection, often the result of a carious tooth, in persons with a high degree of tissue resistance; results in a localised radio-opacity. Synonym: focal condensing osteitis. (05 Mar 2000) |
| primary sclerosing cholangitis | <radiology> Idiopathic, associated with IBD (50%), usually UC, M more than F, peak age 20-30 years of age, chronic inflammation and fibrosis of all bile ducts, stricture, obstruction, abscess (string of beads), intramural pseudo-diverticula, cholangiocarcinoma (10%!!), dilatation proximal to stricture may signal carcinoma Differential diagnosis: cholangiocarcinomarcinoma (diffuse form), primary biliary cirrhosis (PBC), AIDS-related cholangitis (? due to CMV) (12 Dec 1998) |
| sclerosing adenosis | A nodular, benign breast lesion occurring most frequently in relatively young women and consisting of hyperplastic distorted lobules of acinar tissue with increased collagenous stroma; the changes may be difficult to distinguish microscopically from carcinoma. Also, a benign nodular microscopic lesion of the prostate consisting of acimar tissue with increased stroma; the basal cell layer shows characteristic smooth muscle metaplasia. Synonym: adenofibrosis, fibrosing adenomatosis, fibrosing adenosis. (05 Mar 2000) |
| sclerosing agent | A compound which acts by irritation of the veinous intimal epithelium; used in the treatment of varicose veins. (05 Mar 2000) |
| sclerosing haemangioma | <tumour> A benign lung or bronchial lesion, often subpleural, sometimes multiple, which forms hyalinised connective tissue. Synonym: fibrous histiocytoma. (05 Mar 2000) |
| sclerosing inflammation | Inflammation leading to extensive formation of fibrous and scar tissue. (05 Mar 2000) |
| sclerosing keratitis | Inflammation of the cornea complicating scleritis; characterised by opacification of the corneal stroma. (05 Mar 2000) |
| sclerosing leukoencephalitis | <neurology> Chronic progressive illness seen in children a few years after measles infection and involving demyelination of the cerebral cortex. Virus apparently persists in brain cells: usually considered a slow virus disease. (18 Nov 1997) |
| sclerosing mastoiditis | A chronic mastoiditis in which the trabeculae are greatly thickened, almost or entirely obliterating the cells. (05 Mar 2000) |