| sclerosing leukoencephalitis | <neurology> Chronic progressive illness seen in children a few years after measles infection and involving demyelination of the cerebral cortex. Virus apparently persists in brain cells: usually considered a slow virus disease. (18 Nov 1997) |
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| subacute sclerosing leukoencephalitis | <neurology> Chronic progressive illness seen in children a few years after measles infection and involving demyelination of the cerebral cortex. Virus apparently persists in brain cells: usually considered a slow virus disease. (18 Nov 1997) |
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| acute epidemic leukoencephalitis | A disease characterised by acute onset of fever, followed by convulsions, delirium, and coma, and associated with perivascular demyelination and haemorrhagic foci in the central nervous system. Synonym: acute primary haemorrhagic meningoencephalitis, Strumpell's disease. (05 Mar 2000) |
| acute haemorrhagic leukoencephalitis | A fulminating demyelinating disorder of the central nervous system that affects mainly children and young adults. Almost always preceded by a respiratory infection, characterised by the abrupt onset of fever, headache, confusion, and nuchal rigidity, soon followed by focal seizures, hemiplegia, or quadriplegia, brainstem findings, and coma; the CSF shows evidence of an inflammatory process; due to the massive destruction of the white matter of one or both hemispheres, often accompanied by similar destruction of the white matter of the brainstem and cerebellar peduncles; of unknown aetiology. Synonym: acute haemorrhagic leukoencephalitis, acute necrotizing haemorrhagic leukoencephalitis. (05 Mar 2000) |
| acute necrotizing haemorrhagic leukoencephalitis | A fulminating demyelinating disorder of the central nervous system that affects mainly children and young adults. Almost always preceded by a respiratory infection, characterised by the abrupt onset of fever, headache, confusion, and nuchal rigidity, soon followed by focal seizures, hemiplegia, or quadriplegia, brainstem findings, and coma; the CSF shows evidence of an inflammatory process; due to the massive destruction of the white matter of one or both hemispheres, often accompanied by similar destruction of the white matter of the brainstem and cerebellar peduncles; of unknown aetiology. Synonym: acute haemorrhagic leukoencephalitis, acute necrotizing haemorrhagic leukoencephalitis. (05 Mar 2000) |
| leukoencephalitis | Encephalitis restricted to the white matter. (05 Mar 2000) |
| leukoencephalitis, acute haemorrhagic | A rare, fatal postinfection or allergic demyelinating disease of the central nervous system having a fulminating course and occurring mainly in young adults. It is characterised by destruction of white matter to the point of liquefaction; widespread necrosis of blood vessel walls leading to the formation of multiple small haemorrhages in the involved areas and the exudation of fibrin into the surrounding tissue; and cellular infiltration of the necrotic areas. (12 Dec 1998) |
| radial sclerosing lesion | A variant of sclerosing adenosis of the breast with central scar formation and radiating hyperplastic ducts. Synonym: radial scar. (05 Mar 2000) |
| cholangitis, sclerosing | Chronic, nonbacterial inflammatory narrowing of the bile ducts. About 50% of the cases are associated with ulcerative colitis. Treatment is to relieve the obstruction by balloon dilatation or surgery. (12 Dec 1998) |
| chronic diffuse sclerosing osteomyelitis | A proliferative reaction of bone to a low-grade infection of the jaws; most often seen in middle-aged or older black women as extensive, often bilateral radio-opacities of the mandible and maxilla. (05 Mar 2000) |
| chronic focal sclerosing osteomyelitis | A reaction of bone to a mild bacterial infection, often the result of a carious tooth, in persons with a high degree of tissue resistance; results in a localised radio-opacity. Synonym: focal condensing osteitis. (05 Mar 2000) |
| primary sclerosing cholangitis | <radiology> Idiopathic, associated with IBD (50%), usually UC, M more than F, peak age 20-30 years of age, chronic inflammation and fibrosis of all bile ducts, stricture, obstruction, abscess (string of beads), intramural pseudo-diverticula, cholangiocarcinoma (10%!!), dilatation proximal to stricture may signal carcinoma Differential diagnosis: cholangiocarcinomarcinoma (diffuse form), primary biliary cirrhosis (PBC), AIDS-related cholangitis (? due to CMV) (12 Dec 1998) |
| sclerosing adenosis | A nodular, benign breast lesion occurring most frequently in relatively young women and consisting of hyperplastic distorted lobules of acinar tissue with increased collagenous stroma; the changes may be difficult to distinguish microscopically from carcinoma. Also, a benign nodular microscopic lesion of the prostate consisting of acimar tissue with increased stroma; the basal cell layer shows characteristic smooth muscle metaplasia. Synonym: adenofibrosis, fibrosing adenomatosis, fibrosing adenosis. (05 Mar 2000) |
| sclerosing agent | A compound which acts by irritation of the veinous intimal epithelium; used in the treatment of varicose veins. (05 Mar 2000) |
| sclerosing haemangioma | <tumour> A benign lung or bronchial lesion, often subpleural, sometimes multiple, which forms hyalinised connective tissue. Synonym: fibrous histiocytoma. (05 Mar 2000) |
| sclerosing inflammation | Inflammation leading to extensive formation of fibrous and scar tissue. (05 Mar 2000) |