| ryanodine | <drug> A drug that blocks the release of calcium from the sarcoplasmic reticulum of skeletal muscle. Ryanodine binding proteins have also been found in the CNS. (17 Dec 1997) |
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| ryanodine receptor calcium release channel | Protein complexes that mediate the release of calcium from the sarcoplasmic reticulum in both skeletal and cardiac muscle cells by forming tetrametric complexes. These complexes each then act as a calcium channel. There are three isoforms of the ryr: ryr1, ryr2, and ryr3. Ryr1 is specifically expressed in skeletal muscles and ryr2 in cardiac muscles. Ryr3 is yet another isoform found in non-muscle cells such as neuronal cells. (12 Dec 1998) |