| retinol | Vitamin A1alcohol; 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene;a half-carotene bearing the b (or beta-ionone) form of the cyclic end group and a CH2OH at the C-15 position (numbering as in carotenoids) or 9'-position (numbering as a nonyl side chain on a cyclohexene ring); an intermediate in the vision cycle, it also plays a role in growth and differentiation. See: dehydroretinol. Synonym: vitamin A1 alcohol, vitamin A1. Retinol dehydrogenase, an oxidoreductase catalyzing interconversion of retinal and NADH to retinol and NAD+. (05 Mar 2000) |
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| retinol 4-hydroxylase | <enzyme> Converts retinol to 4-hydroxyretinol in presence of NADPH Registry number: EC 1.14.13.- (26 Jun 1999) |
| retinol-binding protein | <molecular biology> Proteins which bind with retinol. The retinol-binding protein found in plasma has an alpha-1 mobility on electrophoresis and a molecular weight of 21,000-22,000. The protein has one binding site for retinol and is responsible for the transport of vitamin A. The retinol- protein complex (molecular weight 80,000 to 90,000) circulates in plasma in the form of a protein-protein complex with prealbumin. The retinol-binding protein found in tissue has a molecular weight of 14,000 and carries retinol as a non-covalently-bound ligand. (03 Jul 1999) |
| retinol dehydratase | <enzyme> Catalyses conversion of retinol to anhydroretinol; isolated from spodoptera frugiperda; genbank u28654 Registry number: EC 4.2.1.- (26 Jun 1999) |
| retinol dehydrogenase | <enzyme> 9-cis-retinol dehydrogenase is also available Registry number: EC 1.1.1.105 Synonym: 11-cis retinol dehydrogenase, p32 retinol dehydrogenase (26 Jun 1999) |
| retinol isomerase | <enzyme> Catalyses the isomerization of all trans-retinol to 11-cis-retinol in the dark; found in the pigment epithelium in the eye Registry number: EC 5.2.1.7 Synonym: retinoid isomerase (26 Jun 1999) |
| 11-cis-retinol | Retinol with cis configuration at the 11-position (carotenoid numbering) or 5'-position (retinol numbering) of the side chain; an intermediate in the vision cycle. Synonym: neoretinene B. (05 Mar 2000) |
| 9-cis-retinol dehydrogenase | <enzyme> Catalyses oxidation of 9-cis-retinol to 9-cis-retinaldehyde; does not catalyze oxidation of all-trans-retinol; genbank u89717 Registry number: EC 1.1.1.- Synonym: retinol dehydrogenase (9-cis) (26 Jun 1999) |
| lecithin-retinol acyltransferase | <enzyme> Transfers 1-acyl moiety from lecithin to retinol-cellular retinol-binding protein, type II, to produce retinyl esters; does not use CoA Registry number: EC 2.3.1.- (26 Jun 1999) |