retino : KMLE 의학 검색 엔진 - 의학사전, 의학용어, 의학약어, 의학논문, 약품/의약품 검색

MeSH(Medical Subject Headings) 맞춤 검색 (http://www.nlm.nih.gov) 결과 : 5 페이지: 1

Retinoblastoma - 새창 A malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. The tumor tends to occur in early childhood or infancy and may be present at birth. The majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS, PATHOLOGIC; STRABISMUS; and visual loss represent common clinical characteristics of this condition. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2104)
Synonyms : Familial Retinoblastoma, Hereditary Retinoblastoma, Sporadic Retinoblastoma, Familial Retinoblastomas, Glioblastomas, Retinal, Gliomas, Retinal, Hereditary Retinoblastomas, Neuroblastomas, Retinal, Retinal Glioblastoma, Retinal Glioblastomas, Retinal Glioma
Retinoblastoma Protein - 새창 Product of the retinoblastoma tumor suppressor gene. It is a nuclear phosphoprotein hypothesized to normally act as an inhibitor of cell proliferation. Rb protein is absent in retinoblastoma cell lines. It also has been shown to form complexes with the adenovirus E1A protein, the SV40 T antigen, and the human papilloma virus E7 protein.
Synonyms : Rb Gene Product, Rb1 Gene Product, Retinoblastoma Nuclear Phosphoprotein p105 Rb, p105 Rb Protein
Retinoblastoma-Like Protein p107 - 새창 A negative regulator of the CELL CYCLE that undergoes PHOSPHORYLATION by CYCLIN-DEPENDENT KINASES. It contains a conserved pocket region that binds E2F4 TRANSCRIPTION FACTOR and interacts with viral ONCOPROTEINS such as POLYOMAVIRUS TUMOR ANTIGENS; ADENOVIRUS E1A PROTEINS; and PAPILLOMAVIRUS E7 PROTEINS.
Synonyms : RBL1 Protein, Retinoblastoma Like Protein p107, p107 Tumor Suppressor Protein, Retinoblastoma Like Protein 1, p107, Retinoblastoma-Like Protein
Retinoblastoma-Like Protein p130 - 새창 A negative regulator of the CELL CYCLE that undergoes PHOSPHORYLATION by CYCLIN-DEPENDENT KINASES. RBL2 contains a conserved pocket region that binds E2F4 TRANSCRIPTION FACTOR and E2F5 TRANSCRIPTION FACTOR. RBL2 also interacts with viral ONCOPROTEINS such as POLYOMAVIRUS TUMOR ANTIGENS; ADENOVIRUS E1A PROTEINS; and PAPILLOMAVIRUS E7 PROTEINS.
Synonyms : RBL2 Protein, Retinoblastoma Like Protein p130, Retinoblastoma Like Protein 2, p130, Retinoblastoma-Like Protein
Retinoid X Receptor alpha - 새창 A nuclear transcription factor. Heterodimerization with PPAR GAMMA is important in regulation of GLUCOSE metabolism and CELL GROWTH PROCESSES.
Synonyms : RXR alpha Receptor, Receptor, RXR alpha