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replicator The specific site of a bacterial genome (chromosome) at which replication begins.
(05 Mar 2000)
genetic locus <genetics> The position of a gene in a linkage map or on a chromosome.
(18 Nov 1997)
marker locus A locus on a chromosome or in a stretch of DNA that can be identified (e.g., a restriction fragment length polymorphism) and can serve in linkage analysis and in the isolation of a disease gene.
See: linkage marker.
(05 Mar 2000)
cis-acting locus A section of DNA that affects the activity of DNA sequences on that same molecule of DNA.
(05 Mar 2000)
complex locus A set of closely linked genetic loci with a common function, as in the major histocompatibility complex locus.
(05 Mar 2000)
W locus <molecular biology> Mouse coat colour locus, equivalent to the kit proto-oncogene, that encodes a receptor tyrosine kinase essential for development of haemopoietic and germ cells.
(18 Nov 1997)
multi locus enzyme electrophoresis Inhibition of translation of the transcript of a transposase gene by a multicopy plasmid with suitable inhibitory gene. The plasmid inhibits transposition events in the host bacterium.
(18 Nov 1997)
multi-locus probe A probe that hybridizes to anumber of different sites in the genome of an organism.
(09 Oct 1997)
X-linked locus Any locus that in normal karyotypes is borne on the X chromosome.
(05 Mar 2000)
sex-linked locus Any locus that in normal karyotypes is borne on a heterosome; commonly but incorrectly applied to an X-linked locus.
(05 Mar 2000)
Y-linked locus Any (haploid) locus that in normal karyotypes is borne on the Y chromosome. The known content is so far small.
(05 Mar 2000)
locus <genetics> The site in a linkage map or on a chromosome where the gene for a particular trait is located. Any one of the alleles of a gene may be present at this site.
(18 Nov 1997)
locus ceruleus A shallow depression, of a blue colour in the fresh brain, lying laterally in the most rostral portion of the rhomboidal fossa near the cerebral aqueduct; it lies near the lateral wall of the fourth ventricle and consists of about 20,000 melanin-pigmented neuronal cell bodies whose norepinephrine-containing axons have a remarkably wide distribution in the cerebellum as well as in the hypothalamus and cerebral cortex.
Synonym: substantia ferruginea, locus cinereus, locus ferrugineus.
(05 Mar 2000)
locus cinereus A shallow depression, of a blue colour in the fresh brain, lying laterally in the most rostral portion of the rhomboidal fossa near the cerebral aqueduct; it lies near the lateral wall of the fourth ventricle and consists of about 20,000 melanin-pigmented neuronal cell bodies whose norepinephrine-containing axons have a remarkably wide distribution in the cerebellum as well as in the hypothalamus and cerebral cortex.
Synonym: substantia ferruginea, locus cinereus, locus ferrugineus.
(05 Mar 2000)
locus coeruleus Bluish region in the superior angle of the fourth ventricle floor, corresponding to melanin-like pigmented nerve cells which lie lateral to the ponto-mesencephalic central gray (griseum centrale). It is also known as nucleus pigmentosus pontis, locus cinereus, and locus ferrugineus.
(12 Dec 1998)
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