| sickness impact profile | A quality-of-life scale developed in the united states in 1972 as a measure of health status or dysfunction generated by a disease. It is a behaviourally based questionnaire for patients and addresses activities such as sleep and rest, mobility, recreation, home management, emotional behaviour, social interaction, and the like. It measures the patient's perceived health status and is sensitive enough to detect changes or differences in health status occurring over time or between groups. (12 Dec 1998) |
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| draft environmental impact statement | (DEIS) A draft statement of environmental effects. Section 102 of the National Environmental Policy Act requires a DEIS for all major federal actions. The DEIS is released to the public and other agencies for comment and review. (05 Dec 1998) |
| impact | 1. Contact or impression by touch; collision; forcible contact; force communicated. "The quarrel, by that impact driven." (Southey) 2. <mechanics> The single instantaneous stroke of a body in motion against another either in motion or at rest. Source: Websters Dictionary (01 Mar 1998) |
| impact fusion | <radiobiology> Fusion approach where a fuel projectile is acclerated and impacted into either a stationary target or another projectile. This is valuable for scientific purposes but not a candidate for a fusion energy source because the likelihood of fusion occurring in a single collision is too low. Multiple accelerated pellets colliding with spherical symmetry might be a viable inertial confinement approach. An impact fusion driver accelerates the macroparticles and is used in inertial confinement fusion. (13 Nov 1997) |
| impact resistance | The ability of a lens for eyewear to withstand impact without shattering or breaking, i.e., of a 3/8 -inch steel ball dropped 50 feet; criteria for determination of impact resistance are specified by U.S. Regulations. (05 Mar 2000) |
| environmental impact statement | (EIS; FEIS) A statement of the environmental effects of a proposed action and of alternative actions. Section 102 of the National Environmental Policy Act (NEPA) requires an EIS for all major federal actions. (05 Dec 1998) |
| ANK repeat | <molecular biology> Amino acid motif found in diverse proteins including ankyrins (hence the name), the notch product, transcriptional regulators, cell cycle regulatory proteins and a toxin produced by the black widow spider. The motif is about 33 amino acids long and is generally found as a tandem array of 2-7 repeats, though ankyrins contain 24 repeats. Their role is not established, but they may be involved in protein protein binding. (18 Nov 1997) |
| ankyrin repeat | Protein domains that contain 33-amino acid long sequences that often occur in tandem arrays. This repeating sequence of 33-amino acids was discovered in ankyrin and is involved in interaction with the anion exchanger (band 3 protein) and may perform a role in molecular recognition in diverse proteins. (12 Dec 1998) |
| cesarean section, repeat | Extraction of the foetus by abdominal hysterotomy anytime following a previous cesarean. (12 Dec 1998) |
| heptad repeat | <molecular biology> A heptad repeat is a type of tandem repeat sequence. It is a sequence of seven amino acids which is repeated multiple times in a row within certain proteins (the intermediate filament proteins) of nearly every animal in the animal kingdom. (09 Oct 1997) |
| HIV long-terminal repeat | Regulatory sequences important for viral replication that are located on each end of the HIV genome. The ltr includes the HIV enhancer, promoter, and other sequences. Specific regions in the ltr include the negative regulatory element (nre), nf-kappa b binding sites , sp1 binding sites, tata box, and trans-acting responsive element (tar). The binding of both cellular and viral proteins to these regions regulates HIV transcription. (12 Dec 1998) |
| direct terminal repeat | A particular sequence of nucleotides which appears on both ends of a DNA or RNA molecule. (09 Oct 1997) |
| inverted repeat | Either of two copies of a DNA sequence (such as those foundat oppositeends of a transposon) whichoccur in identical but inverted form. (09 Oct 1997) |
| tandem repeat | <molecular biology> Copies of genes repeated one after another along a chromosome: for example the 40S rRNA genes in somatic cells of toads, of which there are about 500 copies. (18 Nov 1997) |
| tandem repeat sequence | <molecular biology> Multiple copies of the same base sequence on a chromosome, used as a marker in physical mapping. (09 Oct 1997) |