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  • cellular oncogene
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  • oncogene
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  • signaling oncogene
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  • oncogene
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  • cellular oncogene
    ¼¼Æ÷Á¾¾çÀ¯ÀüÀÚ
  • oncogene
    Á¾¾çÀ¯ÀüÀÚ, Á¾¾ç¿ø
  • signaling oncogene
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  • ras gene
    ras À¯ÀüÀÚ(¡­ë¶îîí­)
  • ras protein
    ras ´Ü¹é(¡­Ó±ÛÜ)
  • Erb-A oncogene
    Erb-A ¾ÏÀ¯ÀüÀÚ
  • Erb-B oncogene
    Erb-B ¾ÏÀ¯ÀüÀÚ
  • Fins oncogene
    Fins ¾ÏÀ¯ÀüÀÚ
  • proto-oncogene
    ¿øÁ¾¾çÀ¯ÀüÀÚ
  • proto-oncogene
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  • proto-oncogene
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  • ras gene
    ras À¯ÀüÀÚ(¡­ë¶îîí­)
  • ras protein
    ras ´Ü¹é(¡­Ó±ÛÜ)
  • cellular oncogene
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  • oncogene
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  • oncogene
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  • proto-oncogene
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  • proto-oncogene
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  • proto-oncogene
    ¿ø¹ß¾ÏÀ¯ÀüÀÚ(ê«Û¡äßëºîîí­)
  • trk proto-oncogene
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  • ras gene
    ras À¯ÀüÀÚ(ë¶îîí­)
  • cellular oncogene
    ¼¼Æ÷ ¾ÏÀ¯ÀüÀÚ(á¬øàäßë¶îîí­)
  • oncogene
    ¾ÏÀ¯ÀüÀÚ(äßë¶îîí­)
  • oncogene theory
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RAS   1) Reticular Activating(Activation) System
  2) Renal Artery Stenosis
RAS rapid atrial stimulation; recurrent aphthous stomatitis; reflex activating stimulus; reliability, av...
ras retrovirus-associated DNA sequence
GnRH Gonadotropin Releasing Hormone  [HP 1898, 2034]
  = LHRH
  = Go...
AXL anexelekto [oncogene]; axillary lymphoscintigraphy
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Ras GAP Ras GTPase activating protein
Ras p21(ras
c-onc cellular oncogene
GRO-alpha Growth Regulated Oncogene-alpha
GROalpha Growth-related oncogene-alpha
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  • cellular oncogene
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  • Ras.
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    L. rasuraeÀÇ ¾àÀÚ
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proto-oncogene protein p21(ras) Cellular protein encoded by the c-ras genes. The protein has GTPase activity and is involved in transmembrane signal transduction as a guanine nucleotide binding protein. Elevated levels of p21 c-ras have been associated with neoplasia.
(12 Dec 1998)
oncogene protein p21(ras) Transforming protein encoded by ras oncogenes. Point mutations in the cellular ras gene (c-ras) can also result in a mutant p21 protein that can transform mammalian cells. Oncogene protein p21(ras) has been directly implicated in human neoplasms, perhaps accounting for as much as 15-20% of all human tumours.
(12 Dec 1998)
p21(ras) farnesyl-protein transferase <enzyme> Transfers the farnesyl moiety from farnesyl pyrophosphate to a cysteine in p21(ras) proteins; composed of an alpha and a beta subunit
Registry number: EC 2.5.1.-
Synonym: farnesyl-protein transferase p21(ras), ras p21 farnesyl-protein transferase, protein-cysteine farnesyltransferase, pc farnesyltransferase, protein farnesyltransferase, p21(ras) farnesyltransferase, farnesyl-protein transferase-alpha, farnesyl-protein transferase-beta, ft alpha, ft beta, caax farnesyltransferase, ftase enzyme
(26 Jun 1999)
ras <oncogene> One of a family of oncogenes, first identified as transforming genes of Harvey and Kirsten murine sarcoma viruses. (Name from rat sarcoma because Harvey virus, though a mouse virus, obtained its transforming gene during passage in a rat). Transforming protein coded is p21ras, a GTP-binding protein with GTPase activity, that resembles regulatory G-proteins.
(18 Nov 1997)
ras protein geranylgeranyltransferase <enzyme> Mammalian enzyme transfers geranylgeranyl groups to a cysteine residue fourth from the c-terminal group of a p21 ras protein, prefers leucine at the cooh terminus; see also rhoa geranylgeranyltransferase and protein geranylgeranyltransferase
Registry number: EC 2.5.1.-
Synonym: geranylgeranyltransferase ras protein, ras protein gg transferase, ggtase I, caax geranylgeranyl transferase
(26 Jun 1999)
ras proteins Small GTP-binding proteins encoded by ras genes (genes, ras) that play a critical role in normal cellular growth, differentiation, and development, and have the potential for malignant transformation. Two of the major ras proteins include the normal cellular form, proto-oncogene protein p21(ras), and the malignant form, oncogene protein p21(ras).
(12 Dec 1998)
genes, ras Family of retrovirus-associated DNA sequences (ras) originally isolated from harvey (h-ras, ha-ras, rash) and kirsten (k-ras, ki-ras, rask) murine sarcoma viruses. Ras genes are widely conserved among animal species and sequences corresponding to both h-ras and k-ras genes have been detected in human, avian, murine, and non-vertebrate genomes. The closely related n-ras gene has been detected in human neuroblastoma and sarcoma cell lines. All genes of the family have a similar exon-intron structure and each encodes a p21 protein.
(12 Dec 1998)
h-ras <oncogene> A point-mutated proto-oncogene that is found in melanoma and in carcinoma of colon, lung and pancreatic tissue.
(10 Oct 1997)
k-ras <oncogene> A proto-oncogene that has point mutations and is associated with melanoma, thyroid carcinoma, and acute myelogenous and lymphoblastic leukaemia.
(09 Oct 1997)
recessive oncogene <molecular biology> A single copy of this gene issufficient to suppress cell proliferation, the loss of both copies of the gene contributes to cancer formation.
(09 Oct 1997)
viral oncogene <molecular biology> A viral gene that contributes to cancer development in vertebrate hosts.
(09 Oct 1997)
cellular oncogene <molecular biology> A normal gene that, when mutated or improperly expressed, can cause cancer to develop.
(09 Oct 1997)
c-oncogene <molecular biology> A normal gene which has a tumour-producing insert that may have originated from a virus in it, turning it into a proto-oncogene.
When these genes are sufficiently mutated, amplified, or over-expressed (transcribed too many times), they can begin to produce cancers.
(05 Jan 1998)
proto-oncogene <molecular biology> The normal, cellular equivalent of an oncogene, thus usually a gene involved in the signalling or regulation of cell growth. In general, cellular proto-oncogenes are prefixed with a c, rather than their abnormal viral counterparts, that are prefixed with a v, for example c myc and v myc.
They are fragments of DNA, related to oncogenes but are the normal switches used to control growth and tissue repair.
(06 Oct 1997)
proto-oncogene protein pp60(c-src) <enzyme> Membrane-associated tyrosine-specific kinase encoded by the c-src genes. It has an important role in cellular growth control. Truncation of carboxy-terminal residues in pp60(c-src) leads to pp60(v-src) which has the ability to transform cells. This kinase pp60 c-src should not be confused with csk, also known as c-src kinase.
Registry number: EC 2.7.1.-
(12 Dec 1998)
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