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quenching 1. extinguishing, suppressing, or diminishing a physical property, as the rapid chilling of a hot metal by plunging it into cold liquid.  2. in biochemistry, decrease of fluorescence from an excited molecule by interference that reduces the fluorescence intensity, such as deexcitation of the fluorescent molecule by collision with other molecules, absorption of fluorescent emission by the surrounding medium, or a decrease or shift in wavelength of fluorescence due to chemical interaction of the fluorescent molecule with other molecules.  3. in liquid scintillation counting, interference with generation or propagation of light energy from the sample, decreasing the counting efficiency of the detector.  4. the termination of secondary and subsequent ionizations in a detector to give it time to become sensitive again.
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