| pyruvate kinase deficiency |
A hereditary deficiency of the enzyme pyruvate kinase. Pyruvate kinase deficiency results in hemolytic anemia.
출처: www.nutrabio.com/Definitions/definitions_p.htm
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| pyruvate kinase |
[EC 2.7.1.40] an enzyme of the transferase class that catalyzes the transfer of high energy phosphate from phosphoenolpyruvate to ADP to yield ATP and pyruvate; it is one of two reactions generating ATP in the Embden-Meyerhof pathway (see illustration at pathway) and a key regulatory site in this pathway. The enzyme has three distinct isozymes. Deficiency of pyruvate kinase activity in erythrocytes, an autosomal recessive trait, results in hemolytic anemia.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| pyruvate kinase (PK) deficiency |
deficiency of the erythrocytic isozyme of pyruvate kinase, the most common glycolytic enzyme defect in the Embden-Meyerhof pathway; deficient product (ATP) causes chronic hemolytic anemia of widely variable severity. PK deficiency is an autosomal recessive trait and has no distinguishing clinical features from the other hemolytic disorders.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| pyruvate kinase deficiency |
hereditary blood disorder characterized by a deficiency of the enzyme pyruvate kinase. physical findings associated with the disorder may include reduced levels of oxygen-carrying hemoglobulin in the blood due to premature destruction of red blood cells (hemolytic anemia); abnormally increased levels of bilirubin in the blood (hyperbilirubinemia); abnormal enlargement of the spleen (splenomegaly); and/or other abnormalities.
출처: ipp.boku.ac.at/pz/ref/glossar1.html
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