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Baker's pyridine extraction Hot pyridine treatment of tissues fixed in dilute Bouin's fixative, used to extract phospholipids from tissues as a control in the histochemical staining of this material.
(05 Mar 2000)
pyridine <physiology> A nitrogenous base, C5H5N, obtained from the distillation of bone oil or coal tar, and by the decomposition of certain alkaloids, as a colourless liquid with a peculiar pungent odour. It is the nucleus of a large number of organic substances, among which several vegetable alkaloids, as nicotine and certain of the ptomaines, may be mentioned. See Lutidine.
Origin: From Gr. Fire.
Source: Websters Dictionary
(01 Mar 1998)
adenine nucleotide A condensation product of adenosine and phosphoric acid; a nucleotide found among the hydrolysis products of all nucleic acids. 3'-Adenylic acid (adenosine 3'-monophosphate) and 5'-adenylic acid (adenosine 5'-monophosphate) differ in the place of attachment of the phosphoric acid to the d-ribose; deoxyadenylic acid differs in having H instead of OH at the 2' position of d-ribose.
See: AMP.
Synonym: adenine nucleotide.
(05 Mar 2000)
adenine nucleotide translocase <enzyme> Catalyses the exchange between endogenous and exogenous adenine nucleotides in mitochondria.ec 2.7.7.-.
Registry number: EC 2.7.7.-
(12 Dec 1998)
cyclic nucleotide A nucleoside monophosphate in which the phosphoryl group is linked twice to the sugar moiety; e.g., adenosine 3',5'-cyclic monophosphate (cAMP).
(05 Mar 2000)
cyclic nucleotide-regulated protein kinases <enzyme> A group of enzymes that catalyses the phosphorylation of serine or threonine residues of proteins and is dependent on cyclic nucleotides.
Registry number: EC 2.7.10.-
(12 Dec 1998)
xanthine nucleotide The monophosphoric ester of xanthosine. An intermediate in GMP biosynthesis.
Synonym: xanthidylic acid, xanthine nucleotide, xanthylic acid.
(05 Mar 2000)
pyrimidine-5'-nucleotide nucleosidase <enzyme> Also acts on some deoxyribonucleotides
Registry number: EC 3.2.2.10
Synonym: pyr-5'-nt-nucleosidase
(26 Jun 1999)
nicotinamide-nucleotide adenylyltransferase <enzyme> An enzyme that catalyses reversibly the transfer of the adenylyl moiety of ATP to the phosphoryl group of nmn to form NAD+ and pyrophosphate. The enzyme is found predominantly in the nuclei and catalyses the final reaction in the major pathway for the biosynthesis of NAD in mammals.
Chemical name: ATP:nicotinamide-nucleotide adenylyltransferase
Registry number: EC 2.7.7.1
(12 Dec 1998)
nucleotide <biochemistry> Phosphate esters of nucleosides. The metabolic precursors of nucleic acids are monoesters with phosphate on carbon 5 of the pentose (known as 5' to distinguish sugar from base numbering).
However many other structures, such as adenosine 3'5' cyclic monophosphate (cAMP) and molecules with 2 or 3 phosphates are also called nucleotides.
(18 Nov 1997)
nucleotide 3'-pyrophosphokinase-2',3'-cyclic monophosphokinase <enzyme> Transfers 5'-beta,gamma-pyrophosphate from ATP and some ATP derivatives to nucleotides and nucleosides at the 3'-hydroxyl group; synthesises the respective 3'-pyrophosphoryl nucleotides
Registry number: EC 2.7.6.-
Synonym: ppkase
(26 Jun 1999)
nucleotide binding fold Protein motif consisting of a fold or pocket with certain conserved residues, required for the binding of nucleotides.
(18 Nov 1997)
nucleotide deaminases <enzyme> Catalyze the hydrolysis of nucleotides with the elimination of ammonia.
Registry number: EC 3.5.4
(12 Dec 1998)
nucleotide deletion Deletion of a single nucleotide, which in a transcribed gene will lead to a frameshift mutation.
Synonym: point deletion.
(05 Mar 2000)
nucleotide mapping Two-dimensional separation and analysis of nucleotides.
(12 Dec 1998)
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