| palmoplantar keratoderma | The occurrence of symmetrical diffuse or patchy areas of hypertrophy of the horny layer of the epidermis on the palms and soles; a group of ectodermal dysplasias of considerable variety, and either autosomal dominant or recessive inheritance. Synonym: ichthyosis palmaris et plantaris, keratoderma palmaris et plantaris, keratoderma symmetrica, keratoma plantare sulcatum, keratosis palmaris et plantaris, tylosis palmaris et plantaris. (05 Mar 2000) |
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| keratoderma, palmoplantar | Group of mostly hereditary disorders characterised by thickening of the palms and soles as a result of excessive keratin formation leading to hypertrophy of the stratum corneum (hyperkeratosis). (12 Dec 1998) |
| keratoderma, palmoplantar, diffuse | An autosomal dominant disorder characterised by a widely distributed, well-demarcated hyperkeratosis of the palms and soles. There is more than one genotypically distinct form, each of which is clinically similar but histologically distinguishable. Diffuse palmoplantar keratoderma is distinct from palmoplantar keratoderma (keratoderma, palmoplantar), as the former exhibits autosomal dominant inheritance and hyperhidrosis is frequently present. (12 Dec 1998) |
| punctate | <dermatology> Marked with dots. (09 Oct 1997) |
| punctate basophilia | 1. A speckling of a blood cell or other structure with fine dots when exposed to the action of a basic stain, due to the presence of free basophil granules in the cell protoplasm. Synonym: punctate basophilia. 2. An orange peel appearance of the attached gingiva. 3. A roughening of the surfaces of a denture base to stimulate natural gingival stippling. (05 Mar 2000) |
| punctate cataract | An incomplete cataract in which there are opaque dots scattered through the lens. (05 Mar 2000) |
| punctate haemorrhage | Capillary haemorrhage into the skin that forms petechiae. Synonym: punctate haemorrhage. (05 Mar 2000) |
| punctate hyalosis | A condition marked by minute opacities in the vitreous. (05 Mar 2000) |
| punctate keratitis | Inflammatory cells on the corneal endothelium. Synonym: punctate keratitis, keratitis punctata. (05 Mar 2000) |
| punctate keratoderma | Horny papules over the palms, soles, and digits that develop central plugs; seen commonly in blacks. Synonym: keratoma disseminatum, keratosis punctata. (05 Mar 2000) |
| punctate parotiditis | Recurrent or chronic parotiditis with terminal sialectasis, giving a punctate pattern on sialography; associated with epithelial hyperplasia of intralobular ducts, atrophy of acini, and lymphocytic infiltration, characteristic in Sjogren's disease. (05 Mar 2000) |
| punctate retinitis | See: retinopathy punctata albescens. (05 Mar 2000) |
| superficial punctate keratitis | Epithelial punctate keratitis associated with viral conjunctivitis. Synonym: Thygeson's disease. (05 Mar 2000) |
| deep punctate keratitis | Sharply defined opacities in an otherwise clear cornea, occurring in syphilitic iritis. (05 Mar 2000) |
| actinic keratosis | <dermatology> A skin lesion that is abnormally sensitive to the effects of ultraviolet light (sunlight). Thought to be a precancerous skin lesion that is more common in the fair-skinned or elderly individual. Approximately 20% of these skin lesions will develop into squamous cell carcinoma. Prevention includes the use of sun screen agents and the avoidance of drugs (for example tetracyclines) known to cause photosensitivity reactions. Usually a discreet slightly raised, red or pink lesion located on a sun exposed surface. Texture may appear as rough, gritty or scaly. Growths may be biopsied to look for cancer or removed via cryotherapy or electrical cautery. Some topical agents may be used to promote peeling. (27 Sep 1997) |