| proteolipid protein | <protein> Highly conserved membrane protein (30 kD) in myelin. Cellular function obscure but mutations lethal for example jimpy mouse and Pelizaeus Merzbacher disease of man. (18 Nov 1997) |
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| proteolipids | Protein-lipid combinations abundant in brain tissue, but also present in a wide variety of animal and plant tissues. In contrast to lipoproteins, they are insoluble in water, but soluble in a chloroform-methanol mixture. The protein moiety has a high content of hydrophobic amino acids. The associated lipids consist of a mixture of phosphoglycerides, cerebrosides, and sulfatides, while lipoproteins contain phospholipids, cholesterol, and triglycerides. (12 Dec 1998) |
| myelin proteolipid protein | A myelin protein that is the major component of the organic solvent extractable lipoprotein complexes of whole brain. It has been the subject of much study because of its unusual physical properties. It remains soluble in chloroform even after essentially all of its bound lipids have been removed. (12 Dec 1998) |
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