| protein phosphatases | A class of enzymes that catalyze the dephosphorylation of specific phosphorylated proteins. (05 Mar 2000) |
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| ceramide-activated protein phosphatase | <enzyme> Belongs to the heterotrimeric subfamily of the pp2a group of serine-threonine protein phosphatases; involved in ceramide-mediated signal transduction; inhibited by okadaic acid Registry number: EC 3.1.3.- Synonym: ceramide-stimulated phosphatase, capp (enzyme) (26 Jun 1999) |
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| PEP protein tyrosine phosphatase | <enzyme> Pest - pro, glu, ser and thr; an intracellular ptpase expressed primarily by cells of haematopoietic origin; involved in regulating nuclear tyrosine phosphorylation; amino acid sequence has been determined Registry number: EC 3.1.3.- Synonym: pep ptpase, pest-enriched phosphatase, ptp-pest (26 Jun 1999) |
| RLK5-associated protein phosphatase | <enzyme> Associated with serine-threonine receptor-like kinase, rlk5; from arabidopsis thaliana; composed of 3 domains, an amino-terminal signal anchor, a kinase interaction domain and a type 2c protein phosphatase catalytic domain; mw 65 kD; genbank u09505 Registry number: EC 3.1.3.- Synonym: kapp, kinase-associated protein phosphatase (26 Jun 1999) |
| microtubule-associated protein-2 phosphatase | <enzyme> does not fit into any of the classes of protein phosphatases (types 1,2a,2b and 2c) involved in cellular regulation Registry number: EC 3.1.3.- Synonym: map-2 phosphatase (26 Jun 1999) |
| H1-related protein-tyrosine phosphatase | <enzyme> Has tyrosine and threonine/serine phosphatase activities Registry number: EC 3.1.3.- Synonym: vaccinia virus h1-related protein tyrosine phosphatase, vhr ptpase, vh-ptp13 (26 Jun 1999) |
| PP5 protein-serine-threonine phosphatase | <enzyme> Has 4 tetratricopeptide repeat (tpr) motifs; similar to ppt1 protein; do not confuse with the placental protein pp5; amino acid sequence given in first source Registry number: EC 3.1.3.- Synonym: pp5 phosphatase, protein phosphatase 5 (26 Jun 1999) |
| protein-serine-threonine phosphatase | <enzyme> Consider also EC 3.1.3.16 phosphoprotein phosphatases Registry number: EC 3.1.3.- Synonym: serine phosphatase, threonine phosphatase, protein-serine phosphatase, serine-threonine phosphatase (26 Jun 1999) |
| protein-tyrosine-phosphatase | <enzyme> An enzyme group that specifically dephosphorylates phosphotyrosyl residues in selected proteins. Together with protein-tyrosine kinase, it regulates tyrosine phosphorylation and dephosphorylation in cellular signal transduction and may play a role in cell growth control and carcinogenesis. Chemical name: Protein-tyrosine-phosphate phosphohydrolase Registry number: EC 3.1.3.48 (12 Dec 1998) |
| pyp2 protein tyrosine phosphatase | <enzyme> Shares an essential overlapping role with pyp1 ptpase and is 42% identical in sequence in the c-terminal catalytic domain of pyp1; involved in negative regulation of mitosis in fission yeast Registry number: EC 3.1.3.- Synonym: pyp2 ptpase, pyp2 gene product (26 Jun 1999) |
| pyp3 protein tyrosine phosphatase | <enzyme> Acts as mitotic inducer in fission yeast Registry number: EC 3.1.3.- Synonym: pyp3 gene product, pyp3 ptpase (26 Jun 1999) |
| SH protein-tyrosine phosphatase | <enzyme> Has sequence similarity to src-homology region 2 Registry number: EC 3.1.3.- Synonym: sh-ptp3, sh-ptp1, ptp1c, protein-tyrosine-phosphatase 1c, protein tyrosine phosphatase, nonreceptor type 6, ptpn6, shptp1, protein-tyrosine phosphatase shp, shp ptpase, shp-1, shp-2 (26 Jun 1999) |
| SIT4 protein phosphatase | <enzyme> From saccharomyces cerevisiae; functions in late g1 for progression into s phase Registry number: EC 3.1.3.- (26 Jun 1999) |
| stomach cancer-associated protein-tyrosine phosphatase | <enzyme> Human transmembrane-type ptpase expressed in gastric, pancreatic and colourectal cancer cells; consists of 1093 amino acid; mw 200 kD; genbank d15049 Registry number: EC 3.1.3.- Synonym: sap 1 phosphatase (26 Jun 1999) |
| NU-3 protein tyrosine phosphatase | <enzyme> The murine homolog of rat cam tyrosine phosphatase; has an extracellular cell-adhesion-molecule-like domain; mw 211 kD; genbank x82288 Registry number: EC 3.1.3.- Synonym: nu-3 ptp, ptp nu-3 (26 Jun 1999) |
| DIS2 protein phosphatase | <enzyme> A type 1 protein phosphatase; involved in glycogen phosphorylase activation; interacts genetically with the ras-camp pathway; has been sequenced Registry number: EC 3.1.3.- Synonym: dis2 protein, dis2 gene product (26 Jun 1999) |